Multistate Epidemiology of Histoplasmosis, United States, 2011–20141

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Armstrong, Paige A. ; Jackson, Brendan R. ; Haselow, Dirk ; Fields, Virgie ; Ireland, Malia ; Austin, Connie ; Signs, Kimberly ; Fialkowski, Veronica ; Patel, Reema ; Ellis, Peggy ; Iwen, Peter C. ; Pedati, Caitlin ; Gibbons-Burgener, Suzanne ; Anderson, Jannifer ; Dobbs, Thomas ; Davidson, Sherri ; McIntyre, Mary ; Warren, Kimberly ; Midla, Joanne ; Luong, Nhiem ; Benedict, Kaitlin
• Description:
  Histoplasmosis is one of the most common mycoses endemic to the United States, but it was reportable in only 10 states during 2016, when a national case definition was approved. To better characterize the epidemiologic features of histoplasmosis, we analyzed deidentified surveillance data for 2011-2014 from the following 12 states: Alabama, Arkansas, Delaware, Illinois, Indiana, Kentucky, Michigan, Minnesota, Mississippi, Nebraska, Pennsylvania, and Wisconsin. We examined epidemiologic and laboratory features and calculated state-specific annual and county-specific mean annual incidence rates. A total of 3,409 cases were reported. Median patient age was 49 (interquartile range 33-61) years, 2,079 (61%) patients were male, 1,273 (57%) patients were hospitalized, and 76 (7%) patients died. Incidence rates varied markedly between and within states. The high hospitalization rate suggests that histoplasmosis surveillance underestimates the true number of cases. Improved surveillance standardization and surveillance by additional states would provide more comprehensive knowledge of histoplasmosis in the United States.
• Subjects:
  Adolescent Adult Aged Aged, 80 And Over Child Child, Preschool Female Geography, Medical Histoplasma Histoplasmosis/epidemiology Histoplasmosis/history Histoplasmosis/microbiology Histoplasmosis/mortality History, 21st Century Hospitalization Humans Incidence Infant Infant, Newborn Male Middle Aged Public Health Surveillance Synopsis Young Adult

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• Source:
  Emerg Infect Dis. 24(3):425-431.
• Pubmed ID:
  29460731
• Pubmed Central ID:
  PMC5823339
• Document Type:
  Journal Article
• Place as Subject:
  United States
• Location:
  North America
• Volume:
  24
• Issue:
  3
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:da4610518a643c575a170683fab891d8d6a98e3b262592616f83f22619bfd689
• Download URL:
  https://stacks.cdc.gov/view/cdc/52188/cdc_52188_DS1.pdf
• File Type:
  [PDF - 1020.44 KB ]