Whole-Genome Analysis of Mycobacterium tuberculosis from Patients with Tuberculous Spondylitis, Russia

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Chernyaeva, Ekaterina ; Rotkevich, Mikhail ; Krasheninnikova, Ksenia ; Yurchenko, Andrey ; Vyazovaya, Anna ; Mokrousov, Igor ; Solovieva, Natalia ; Zhuravlev, Viacheslav ; Yablonsky, Piotr ; O’Brien, Stephen J.
• Description:
  Whole-genome analysis of Mycobacterium tuberculosis isolates collected in Russia (N = 71) from patients with tuberculous spondylitis supports a detailed characterization of pathogen strain distributions and drug resistance phenotype, plus distinguished occurrence and association of known resistance mutations. We identify known and novel genome determinants related to bacterial virulence, pathogenicity, and drug resistance.
• Subjects:
  Antitubercular Agents/pharmacology Dispatch Drug Resistance, Bacterial Genome, Bacterial Geography Humans Microbial Sensitivity Tests Mutation Mycobacterium Tuberculosis Spondylitis Tuberculosis Virulence Whole Genome Sequencing

  More +
• Source:
  Emerg Infect Dis. 24(3):579-583.
• Pubmed ID:
  29460750
• Pubmed Central ID:
  PMC5823328
• Document Type:
  Journal Article
• Place as Subject:
  Russia
• Location:
  Europe
• Volume:
  24
• Issue:
  3
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:2195258e0c944012209f140957b363a28c15e3d98af63646b6a7e964a58fd99e
• Download URL:
  https://stacks.cdc.gov/view/cdc/52177/cdc_52177_DS1.pdf
• File Type:
  [PDF - 1.80 MB ]