Whole-Genome Analysis of Mycobacterium tuberculosis from Patients with Tuberculous Spondylitis, Russia

Chernyaeva, Ekaterina; Rotkevich, Mikhail; Krasheninnikova, Ksenia; Yurchenko, Andrey; Vyazovaya, Anna; Mokrousov, Igor; Solovieva, Natalia; Zhuravlev, Viacheslav; Yablonsky, Piotr; O’Brien, Stephen J.

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Whole-Genome Analysis of Mycobacterium tuberculosis from Patients with Tuberculous Spondylitis, Russia

Mar 2018
By Chernyaeva, Ekaterina ; Rotkevich, Mikhail ; Krasheninnikova, Ksenia ; ...
Source: Emerg Infect Dis. 24(3):579-583.

[PDF-1.80 MB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Chernyaeva, Ekaterina ; Rotkevich, Mikhail ; Krasheninnikova, Ksenia ; Yurchenko, Andrey ; Vyazovaya, Anna ; ... More +

Chernyaeva, Ekaterina ; Rotkevich, Mikhail ; Krasheninnikova, Ksenia ; Yurchenko, Andrey ; Vyazovaya, Anna ; Mokrousov, Igor ; Solovieva, Natalia ; Zhuravlev, Viacheslav ; Yablonsky, Piotr ; O’Brien, Stephen J. Less -
Description:

Whole-genome analysis of Mycobacterium tuberculosis isolates collected in Russia (N = 71) from patients with tuberculous spondylitis supports a detailed characterization of pathogen strain distributions and drug resistance phenotype, plus distinguished occurrence and association of known resistance mutations. We identify known and novel genome determinants related to bacterial virulence, pathogenicity, and drug resistance.
Subjects:

[+]

Antitubercular Agents/pharmacology Dispatch Drug Resistance, Bacterial Genome, Bacterial Geography Humans Microbial Sensitivity Tests Mutation Mycobacterium Tuberculosis Spondylitis Tuberculosis Virulence Whole Genome Sequencing
Source:

Emerg Infect Dis. 24(3):579-583.
Pubmed ID:

29460750
Pubmed Central ID:

PMC5823328
Document Type:

Journal Article
Place as Subject:

Russia
Location:

Europe
Volume:

24
Issue:

3
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:2195258e0c944012209f140957b363a28c15e3d98af63646b6a7e964a58fd99e
Download URL:

https://stacks.cdc.gov/view/cdc/52177/cdc_52177_DS1.pdf
File Type:

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