Risk assessment for metalworking fluids and cancer outcomes
Advanced Search
Select up to three search categories and corresponding keywords using the fields to the right. Refer to the Help section for more detailed instructions.
 
 
i


Risk assessment for metalworking fluids and cancer outcomes
  • Published Date:

    Jan 12 2018

  • Source:
    Am J Ind Med. 61(3):198-203.
Filetype[PDF-348.41 KB]


Details:
  • Alternative Title:
    Am J Ind Med
  • Personal Author:
  • Description:
    Background Metalworking fluids (MWF) are complex mixtures with dermal and inhalation exposure. Published reports reveal excess cancer risk. Methods Using published findings exposure response was derived for each attributable cancer site. Aggregate excess lifetime risk was estimated by applying a lifetable calculation. Results Cancer sites contributing the most attributable cases were larynx, esophagus, brain, female breast, and uterine cervix. With constant workplace MWF exposure of 0.1 mg/m3 over a 45 years working life, the risk of attributable cancer was 3.7% or, excluding the less certain female cancers, 3.1%. Conclusion Substantial cancer risks occurred at 0.1 mg/m3 MWF, one fourth of the current NIOSH recommended exposure limit for MWF total particulate. Because ingredients in current MWF remain from earlier formulations, it is likely that some MWF carcinogenicity persists today. Although important changes have occurred, newer agents are being continually introduced with little or no knowledge of chronic health risks.
  • Pubmed ID:
    29327473
  • Pubmed Central ID:
    PMC5824980
  • Document Type:
  • Collection(s):
  • Main Document Checksum:
  • File Type:
No Related Documents.

You May Also Like: