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Comparison of two home sleep testing devices with different strategies for diagnosis of OSA
  • Published Date:
    August 19 2017
  • Source:
    Sleep Breath. 22(1):139-147
  • Language:
    English
Filetype[PDF-351.38 KB]


Details:
  • Pubmed ID:
    28823109
  • Pubmed Central ID:
    PMC5818320
  • Description:
    Purpose

    Home sleep testing devices are being widely used in diagnosis/screening for obstructive sleep apnea (OSA). We examined differences in OSA metrics obtained from two devices with divergent home monitoring strategies; the Apnea Risk Evaluation System (ARES™, multiple signals plus forehead reflectance oximetry) and the Nonin WristOx2™ (single channel finger transmission pulse oximeter), compared to differences from night-night variability of OSA.

    Methods

    152 male / 26 female subjects (BMI=30.3±5.6 kg/m2, age=52.5±8.9 yrs) were recruited without regard to OSA symptoms, and simultaneously wore both ARES™ and Nonin WristOx2™ for 2 nights (n=351 nights). Automated analysis of the WristOx2 yielded ODIOx2 (Oxygen Desaturation Index, #≥4% O2 dips/hr) and automated analysis with manual editing of ARES™ yielded AHI4ARES (apneas+hypopneas with ≥4% O2 dips/hr) and RDIARES (apneas+ hypopneas with ≥4% O2 dips/hr or arousal surrogates). Baseline awake oxygen saturation, percent time <90% O2 saturation (% time <90% O2Sat) and O2 signal loss were compared between the two methods.

    Results

    Correlation between AHI4ARES and ODIOx2 was high (ICC=0.9, 95% CI=0.87–0.92, p<0.001, bias±SD=0.7±6.1 events/hr). Agreement values for OSA diagnosis (77–85%) between devices was similar to that seen from night-to-night variability of OSA using a single device. Awake baseline O2 saturation was significantly higher in the ARES™ (96.2±1.6%) than WristOx2™ (92.2±2.1%, p<0.01). There was a significantly lower %time<90% O2Sat reported by the ARES™ compared to WristOx2 (median (IQR) 0.5(0.0, 2.6) vs 2.1(0.3, 9.7), p<0.001) and the correlation was low (ICC=0.2).

    Conclusions

    OSA severity metrics predominantly dependent on change in oxygen saturation and metrics used in diagnosis of OSA (AHI4 and ODI) correlated well across devices tested. However differences in cumulative oxygen desaturation measures (i.e.% time<90% O2Sat) between the devices suggest caution is needed when interpreting this metric particularly in populations likely to have significant hypoxia.

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