and associated risk factors, 2011– 2014
Advanced Search
Select up to three search categories and corresponding keywords using the fields to the right. Refer to the Help section for more detailed instructions.

Search our Collections & Repository

For very narrow results

When looking for a specific result

Best used for discovery & interchangable words

Recommended to be used in conjunction with other fields

Dates

to

Document Data
Library
People
Clear All
Clear All

For additional assistance using the Custom Query please check out our Help Page

i

and associated risk factors, 2011– 2014

Filetype[PDF-338.84 KB]


English
Details Supporting Files You May Also Like

Details:

  • Alternative Title:
    Clin Infect Dis
  • Personal Author:
  • Description:
    Background

    Toxocariasis results from infection with larval stages of a dog and cat intestinal nematode and causes human morbidity. The current US estimate of Toxocara exposure is 13.9% (NHANES III 1988–1994).

    Methods

    We used a multiplex bead based assay (Tc-CTL-1MBA) with purified Toxocara canis antigen to estimate Toxocara antibody seroprevalence in serum of 13,509 persons six years and older from the National Health and Nutrition Examination Survey (NHANES), 2011–2014 and identified seropositivity risk factors. We tested a subset of 500 samples with the T. canis enzyme immunoassay used in NHANES III to estimate prior seroprevalence had samples from NHANES III been tested by Tc-CTL-1MBA.

    Results

    The age standardized estimate of Toxocara seroprevalence was 5.0% (95% confidence interval [CI], 4.2%–5.8%), lower than previously reported even adjusting for increased Tc-CTL-1MBA specificity. Risk factors for seropositivity from multiple logistic regression were older age (odds ratio [OR], 2.1; 95%CI, 1.1–3.9 in persons 50–59 years old; OR, 1.7; 95%CI, 1.0–2.8 in persons 60–69; and OR, 2.6; 95%CI, 1.5–4.7 in persons ≥70 versus persons 6–11), non-Hispanic Black race/Hispanic origin (OR, 1.4; 95%CI, 1.0–2.0) versus non-Hispanic White, male sex (OR, 1.9; 95%CI, 1.6–2.2), living below poverty level (OR, 1.9; 95%CI, 1.4–2.6), households with ≥0.5 persons per room (OR, 1.3; 95%CI, 1.0–1.6), less than college education (OR, 1.9; 95%CI, 1.5–2.4), and birth outside the United States (OR, 3.6; 95%CI, 2.6–5.1).

    Conclusions

    Toxocara seroprevalence estimates in 2011–14 were lower than in a study from NHANES III, 1988–94, but seropositivity risk factors remained the same and should continue to be the focus of prevention efforts.

  • Subjects:
  • Source:
    Clin Infect Dis. 66(2):206-212
  • Pubmed ID:
    29020386
  • Pubmed Central ID:
    PMC5806997
  • Document Type:
    Journal Article
  • Funding:
    CC999999/Intramural CDC HHS/United States
  • Collection(s):
  • Main Document Checksum:
  • Download URL:
  • File Type:

You May Also Like

Checkout today's featured content at stacks.cdc.gov