Cancer in Guam and Hawaii: A Comparison of Two U.S. Island Populations

Details

• Alternative Title:
  Cancer Epidemiol
• Personal Author:
  Hernandez, Brenda Y. ; Bordallo, Renata A. ; Green, Michael D. ; Haddock, Robert L.
• Description:
  Background ; Cancer disparities within and across populations provide insight into the influence of lifestyle, environment, and genetic factors on cancer risk. ; Methods ; Guam cancer incidence and mortality were compared to that of Hawaii using data from their respective population-based, central cancer registries. ; Results ; In 2009-2013, overall cancer incidence was substantially lower in Guam than in Hawaii for both sexes while overall cancer mortality was higher for Guam males. Cervical cancer incidence and prostate cancer mortality were higher in Guam. Both incidence and mortality were higher among Guam men for cancers of the lung & bronchus, liver & intrahepatic bile duct, and nasopharynx; Chamorro men were disproportionately affected by these cancers. Filipinos and Whites in Guam had lower overall cancer incidence compared to Filipinos and Whites in Hawaii. Although breast cancer incidence was significantly lower in Guam compared to Hawaii, women in Guam presented at younger ages and with rarer disease histologies such as inflammatory carcinoma were more prevalent. Guam patients were also diagnosed at younger ages for cancers of bladder, pancreas, colon & rectum, liver & intrahepatic bile duct, lung & bronchus, stomach, non-Hodgkin lymphoma, and leukemia. ; Conclusion ; Smoking, infectious agents, and betel nut chewing appear to be important contributors to the burden of cancer in Guam. Earlier onset of cancer in Guam suggests earlier age of exposure to key risk factors and/or a more aggressive pathogenesis. Contrasting cancer patterns within Guam and between Guam and Hawaii underscore the potential influence of genes, lifestyle, and environmental factors on cancer development and progression.
• Subjects:
  • Article
  • Guam
  • Hawaii
  • Chamorro
  • Native Hawaiian
  • cancer
  • incidence
  • mortality
  • Adult
  • Aged
  More +
• Source:
  Cancer Epidemiol. 50(Pt B):199-206.
• Pubmed ID:
  29120826
• Pubmed Central ID:
  PMC5806134
• Document Type:
  Journal Article
• Funding:
  HHSN261201000037C/CA/NCI NIH HHS/United States ; U58 DP003906/DP/NCCDPHP CDC HHS/United States ; U54 CA143727/CA/NCI NIH HHS/United States ; U58 DP000976/DP/NCCDPHP CDC HHS/United States ; U54 CA143728/CA/NCI NIH HHS/United States ; U56 CA096254/CA/NCI NIH HHS/United States
• Volume:
  50
• Download URL:
  https://stacks.cdc.gov/view/cdc/51665/cdc_51665_DS1.pdf
• File Type:
  [PDF - 460.26 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:4ee6ad0a41aa94d525009d8ea2a71833bd527a102c3c039118f500b5667f2502