Details:

Alternative Title:
Influenza Other Respir Viruses
Publisher's site:
http://dx.doi.org/10.1111/j.1750-2659.2012.00403.x
Personal Author:
Kosasih, Herman ;  , Roselinda ;  , Nurhayati ; Klimov, Alexander ; Xiyan, Xu ; ... More +
Kosasih, Herman ;  , Roselinda ;  , Nurhayati ; Klimov, Alexander ; Xiyan, Xu ; Lindstrom, Stephen ; Mahoney, Frank ; Beckett, Charmagne ; Burgess, Timothy H. ; Blair, Patrick J. ; Uyeki, Timothy M. ; Sedyaningsih, Endang R. Less -
Description:
Longitudinal data are limited about the circulating strains of influenza viruses and their public health impact in Indonesia. We conducted influenza surveillance among outpatients and hospitalized patients with influenza-like illness (ILI) across the Indonesian archipelago from 2003 through 2007.|Demographic, clinical data, and respiratory specimens were collected for 4236 ILI patients tested for influenza virus infection by RT-PCR and viral culture.|Influenza A and B viruses co-circulated year-round with seasonal peaks in influenza A virus activity during the rainy season (December–January). During 2003–2007, influenza viruses were identified in 20·1% (4236 ⁄ 21 030) of ILI patients, including 20·1% (4015 ⁄ 20 012) of outpatients, and 21·7% (221 ⁄ 1018) of inpatients. One H5N1 case was identified retrospectively in an outpatient with ILI. Antigenic drift in circulating influenza A and B virus strains was detected during the surveillance period in Indonesia. In a few instances, antigenically drifted viruses similar to the World Health Organization (WHO) vaccine strains were detected earlier than the date of their designation by WHO.|Influenza A and B virus infections are an important cause of influenza-like illness among outpatients and hospitalized patients in Indonesia. While year-round circulation of influenza viruses occurs, prevention and control strategies should be focused upon the seasonal peak during rainy season months. Ongoing virologic surveillance and influenza disease burden studies in Indonesia are important priorities to better understand the public health impact of influenza in South-East Asia and the implications of influenza viral evolution and global spread.
Subject:
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Adolescent
Adult
Aged
Child
Child, Preschool
Female
Humans
Infant
Influenza, Human
Influenza A Virus
Influenza B Virus
Male
Middle Aged
Part 1
Retrospective Studies
Seasons
Sentinel Surveillance
Young Adult

Source:
Influenza Other Respir Viruses. 7(3):312-320.
Pubmed ID:
22804910
Pubmed Central ID:
PMC5779827
Document Type:
Journal Article
Place as Subject:
Indonesia
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:1e8a83c34678417b1d731e40f52fde7c524f5eb7cf2aadd6cdb87ec76db1e67b
File Type:

Supporting Files

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