Increase in Ocular Syphilis Cases at Ophthalmologic Reference Center, France, 2012–2015

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• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Pratas, Ana Catarina ; Goldschmidt, Pablo ; Lebeaux, David ; Aguilar, Claire ; Ermak, Natalia ; Benesty, Jonathan ; Charlier, Caroline ; Benveniste, Edgar ; Merabet, Lilia ; Sedira, Neila ; Hope-Rapp, Emilie ; Chaumeil, Christine ; Bodaghi, Bahram ; Héron, Emmanuel ; Sahel, José-Alain ; Lortholary, Olivier ; Errera, Marie-Hélène
• Description:
  We describe the frequency, demographic and clinical features, and visual outcomes of ocular syphilis infections observed during 2012-2015 at a tertiary reference center in Paris, France. Twenty-one cases (29 eyes) were identified. The occurrence of ocular syphilis increased from 1 case in 2012 to 5 cases in 2013, 6 cases in 2014, and 9 cases in 2015 (2.22-25.21/1,000 individual patients/year for the period). Among case-patients, an annual 20%-33% were co-infected with HIV. Seventy-six percent of ocular syphilis infections occurred in men who have sex with men. Seventy-five percent of case-patients had a good final visual outcome (best-corrected visual acuity >0.3 logMAR score). Visual outcome was worse for HIV-positive patients than for HIV-negative patients (p = 0.0139). At follow-up, the best visual outcomes were observed in patients whose mean time from first ocular symptom to consultation was 15 days (SD +19 days).
• Subjects:
  Bacterial Infections Epidemiology France Increase In Ocular Syphilis Cases At Ophthalmologic Reference Center, France, 2012–2015 Men Who Have Sex With Men MSM Neurosyphilis Ocular Ophthalmologic Sexually Transmitted Infections Synopsis Syphilis Uveitis

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• Source:
  Emerg Infect Dis. 24(2):193-200.
• Pubmed ID:
  29350138
• Pubmed Central ID:
  PMC5782877
• Document Type:
  Journal Article
• Volume:
  24
• Issue:
  2
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:ef8f156f6da9bdb5843aabf7433dc4a6cbd1d6cc264b95a9307b9e2b9829f2fc
• Download URL:
  https://stacks.cdc.gov/view/cdc/51387/cdc_51387_DS1.pdf
• File Type:
  [PDF - 1.50 MB ]