Trends in Risk of Pregnancy Loss Among US Women, 1990–2011

Details

• Alternative Title:
  Paediatr Perinat Epidemiol
• Personal Author:
  Rossen, Lauren M. ; Ahrens, Katherine A. ; Branum, Amy M.
• Description:
  Background
  
  Pregnancy loss can have physical and psychological consequences for women and their families. Though a previous study described an increase in the risk of self-reported pregnancy loss from 1970 to 2000, more recent examinations from population-based data of US women are lacking.
  
  Methods
  
  We used data from the 1995, 2002, 2006–2010, 2011–2015 National Survey of Family Growth on self-reported pregnancy loss (miscarriage, stillbirth, ectopic pregnancy) among US women (15–44 years) who reported at least one pregnancy conceived during 1990–2011 that did not result in induced termination (n = 20 012 women; n = 42 526 pregnancies). Trends in the risk of self-reported pregnancy loss and early pregnancy loss (<12 weeks) were estimated, separately, by year of pregnancy conception (limited to 1990–2011 to ensure a sufficient sample of pregnancies for each year and maternal age group) using log-Binomial and Poisson models, adjusted for maternal- and pregnancy-related factors.
  
  Results
  
  Among all self-reported pregnancies, excluding induced terminations, the risk of pregnancy loss was 19.7% and early pregnancy loss was 13.5% during 1990–2011. Risk of pregnancy loss increased by a relative 2% (rate ratio [RR] 1.02, 95% confidence interval [CI] 1.01, 1.02) per year in unadjusted models and 1% per year (RR 1.01, 95% CI 1.00, 1.02) during 1990–2011, after adjustment for maternal characteristics and pregnancy-related factors. In general, trends were similar for early pregnancy loss.
  
  Conclusion
  
  From 1990 to 2011, risk of self-reported pregnancy loss increased among US women. Further work is needed to better understand the drivers of this increase in reported pregnancy loss in the US.
  
  
• Subjects:
  Abortion, Spontaneous Adolescent Adult Female Humans Maternal Age Poisson Distribution Pregnancy Racial Groups Retrospective Studies Risk Factors Socioeconomic Factors Young Adult

  More +
• Source:
  Paediatr Perinat Epidemiol. 32(1):19-29
• Pubmed ID:
  29053188
• Pubmed Central ID:
  PMC5771868
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHS/United States
• Place as Subject:
  United States
• Volume:
  32
• Issue:
  1
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:d0718b411e65fadf83883645eacbfa9ab9b5bd1f65719b2b65475d93720092d8
• Download URL:
  https://stacks.cdc.gov/view/cdc/51032/cdc_51032_DS1.pdf
• File Type:
  [PDF - 475.58 KB ]