Details:

Alternative Title:
J Infect Dis
Personal Author:
Erickson, Bobbie R. ; Sealy, Tara K. ; Flietstra, Tim ; Morgan, Laura ; Kargbo, Brima ; ... More +
Erickson, Bobbie R. ; Sealy, Tara K. ; Flietstra, Tim ; Morgan, Laura ; Kargbo, Brima ; Matt-Lebby, Victor E. ; Gibbons, Aridth ; Chakrabarti, Ayan K. ; Graziano, James ; Presser, Lance ; Flint, Mike ; Bird, Brian H. ; Brown, Shelley ; Klena, John D. ; Blau, Dianna M. ; Brault, Aaron C. ; Belser, Jessica A. ; Salzer, Johanna S. ; Schuh, Amy J. ; Lo, Michael ; Zivcec, Marko ; Priestley, Rachael A. ; Pyle, Meredith ; Goodman, Christin ; Bearden, Scott ; Amman, Brian R. ; Basile, Alison ; Bergeron, Éric ; Bowen, Michael D. ; Dodd, Kimberly A. ; Freeman, Molly M. ; McMullan, Laura K. ; Paddock, Christopher D. ; Russell, Brandy J. ; Sanchez, Angela J. ; Towner, Jonathan S. ; Wang, David ; Zemtsova, Galina E. ; Stoddard, Robyn A. ; Turnsek, Maryann ; Guerrero, Lisa Wiggleton ; Emery, Shannon L. ; Stovall, Janae ; Kainulainen, Markus H. ; Perniciaro, Jamie L. ; Mijatovic-Rustempasic, Slavica ; Shakirova, Gulchekhra ; Winter, Jörn ; Sexton, Christopher ; Liu, Feng ; Slater, Kimetha ; Anderson, Raydel ; Andersen, Lauren ; Chiang, Cheng-Feng ; Tzeng, Wen-Pin ; Crowe, Samuel J. ; Maenner, Matthew J. ; Spiropoulou, Christina F. ; Nichol, Stuart T. ; Ströher, Ute Less -
Description:
During the Ebola virus outbreak of 2013-2016, the Viral Special Pathogens Branch field laboratory in Sierra Leone tested approximately 26 000 specimens between August 2014 and October 2015. Analysis of the B2M endogenous control Ct values showed its utility in monitoring specimen quality, comparing results with different specimen types, and interpretation of results. For live patients, blood is the most sensitive specimen type and oral swabs have little diagnostic utility. However, swabs are highly sensitive for diagnostic testing of corpses.
Subject:
[+]
Clinical Laboratory Services
Disease Outbreaks
Ebolavirus
Hemorrhagic Fever, Ebola
Humans
Laboratories
Real-Time Polymerase Chain Reaction
Reverse Transcriptase Polymerase Chain Reaction
RNA, Viral
Sensitivity And Specificity

Source:
J Infect Dis. 214(3):S258-S262.
Pubmed ID:
27587631
Pubmed Central ID:
PMC5769963
Document Type:
Journal Article
Funding:
CC999999/Intramural CDC HHS/United States
Place as Subject:
Africa, Western ; Sierra Leone
Africa, Western ; Sierra Leone Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:c4fb0a3268521c185fd73e342124c1816a96960ac898b3f91dd6ef7e492562e2
File Type:

Supporting Files

• 	nihms913562.nxml	xml
  	nihms913562f1.gif	gif
  	nihms913562f1.jpg	jpeg

More +