Details:

Alternative Title:
J Autism Dev Disord
Personal Author:
Rubenstein, Eric ; Edmondson-Pretzel, Rebecca ; Windham, Gayle C. ; Schieve, Laura A. ; Wiggins, Lisa D. ; ... More +
Rubenstein, Eric ; Edmondson-Pretzel, Rebecca ; Windham, Gayle C. ; Schieve, Laura A. ; Wiggins, Lisa D. ; DiGuiseppi, Carolyn ; Olshan, Andrew F. ; Howard, Annie G. ; Pence, Brian W. ; Young, Lisa ; Daniels, Julie ; Less -
Description:
Autism spectrum disorder (ASD) diagnosis relies on parent-reported and clinician-observed instruments. Sometimes, results between these instruments disagree. The broader autism phenotype (BAP) in parent-reporters may be associated with discordance. Study to Explore Early Development data (N = 712) were used to address whether mothers with BAP and children with ASD or non-ASD developmental disabilities were more likely than mothers without BAP to 'over-' or 'under-report' child ASD on ASD screeners or interviews compared with clinician observation or overall impression. Maternal BAP was associated with a child meeting thresholds on a maternal-reported screener or maternal interview when clinician ASD instruments or impressions did not (risk ratios: 1.30 to 2.85). Evidence suggests acknowledging and accounting for reporting discordances may be important when diagnosing ASD.
Subject:
[+]
Adult
Article
Autism Diagnostic Interview
Autism Diagnostic Observation Schedule
Autism Spectrum Disorder
Broader Autism Phenotype
Case-Control Studies
Child
Child, Preschool
Developmental Disabilities
Female
Humans
Instrument Discordance
Male
Mothers
Phenotype
Physician's Role
Revised
Autism Spectrum Disorder

Source:
J Autism Dev Disord. 47(10):3253-3266.
Pubmed ID:
28748335
Pubmed Central ID:
PMC5728366
Document Type:
Journal Article ;
Funding:
P30 ES010126/ES/NIEHS NIH HHS/United States ; U10 DD000180/DD/NCBDD CDC HHS/United States ; U01 DD000746/DD/NCBDD CDC HHS/United States ; U10 DD000181/DD/NCBDD CDC HHS/United States ; U10 DD000184/DD/NCBDD CDC HHS/United States ; ... More +
P30 ES010126/ES/NIEHS NIH HHS/United States ; U10 DD000180/DD/NCBDD CDC HHS/United States ; U01 DD000746/DD/NCBDD CDC HHS/United States ; U10 DD000181/DD/NCBDD CDC HHS/United States ; U10 DD000184/DD/NCBDD CDC HHS/United States ; U01 DD001210/DD/NCBDD CDC HHS/United States ; U01 DD000498/DD/NCBDD CDC HHS/United States ; U01 DD001205/DD/NCBDD CDC HHS/United States ; U10 DD000182/DD/NCBDD CDC HHS/United States ; Cooperative Agreement Number U10DD000180, Colorado Department of Public Health ; Cooperative Agreement Number U10DD000181, Kaiser Foundation Research Institute (CA); Cooperative Agreement Number U10DD000182, University of Pennsylvania; Cooperative Agreement Number U10DD000183, Johns Hopkins University; Cooperative Agreement Number U10DD000184, University of North Carolina at Chapel Hill; and Cooperative Agreement Number U10DD000498, Michigan State University/Centers for Disease Control and Prevention/; P2C HD050924/HD/NICHD NIH HHS/United States ; U10 DD000183/DD/NCBDD CDC HHS/United States ; 10052/Autism Speaks/United States ; Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:02fb67982956a9ebb78284d8e1465c40b2defcbffe331c84e78bd6394ebae1c5
File Type:

Supporting Files

• 	NIHMS898596-supplement-Supplement.docx	docx
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  	nihms898596f1.gif	gif
  	nihms898596f1.jpg	jpeg

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