Details:

Alternative Title:
Antimicrob Resist Infect Control
Personal Author:
Magiorakos, A. P. ; Burns, K. ; Rodríguez Baño, J. ; Borg, M. ; Daikos, G. ; ... More +
Magiorakos, A. P. ; Burns, K. ; Rodríguez Baño, J. ; Borg, M. ; Daikos, G. ; Dumpis, U. ; Lucet, J. C. ; Moro, M. L. ; Tacconelli, E. ; Simonsen, G. Skov ; Szilágyi, E. ; Voss, A. ; Weber, J. T. ; Less -
Description:
Background Infections with carbapenem-resistant Enterobacteriaceae (CRE) are increasingly being reported from patients in healthcare settings. They are associated with high patient morbidity, attributable mortality and hospital costs. Patients who are “at-risk” may be carriers of these multidrug-resistant Enterobacteriaceae (MDR-E). Methods The guidance was created by a group of experts who were functioning independently of their organisations, during two meetings hosted by the European Centre for Disease Prevention and Control. A list of epidemiological risk factors placing patients “at-risk” for carriage with CRE was created by the experts. The conclusions of a systematic review on the prevention of spread of CRE, with the addition of expert opinion, were used to construct lists of core and supplemental infection prevention and control measures to be implemented for “at-risk” patients upon admission to healthcare settings. Results Individuals with the following profile are “at-risk” for carriage of CRE: a) a history of an overnight stay in a healthcare setting in the last 12 months, b) dialysis-dependent or cancer chemotherapy in the last 12 months, c) known previous carriage of CRE in the last 12 months and d) epidemiological linkage to a known carrier of a CRE. Conclusions Strengthening the microbiological capacity, surveillance and reporting of new cases of CRE in healthcare settings and countries is necessary to monitor the epidemiological situation so that, if necessary, the implemented CRE prevention strategies can be refined in a timely manner. Creating a large communication network to exchange this information would be helpful to understand the extent of the CRE reservoir and to prevent infections in healthcare settings, by applying the principles outlined here. Electronic supplementary material The online version of this article (10.1186/s13756-017-0259-z) contains supplementary material, which is available to authorized users.
Subject:
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Active Screening
AMR
Antimicrobial Resistance
Carbapenem-resistant Enterobacteriaceae
Core Measures
CRE
Guidelines Article
Healthcare-associated Infections
MDR-E
Multidrug-resistant Enterobacteriaceae
Supplemental Measures

Source:
Antimicrob Resist Infect Control. 6. ;
Pubmed ID:
29163939
Pubmed Central ID:
PMC5686856
Document Type:
Journal Article ;
Collection(s):
CDC Public Access
Main Document Checksum:
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urn:sha256:05eb05d9c9a1ca34ee81fd1a91d282bc74bc5bf41924e5a8abedfd528d731d46
File Type:

Supporting Files

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