Relationships between Neighbourhood Characteristics and Current STI Status among HIV-Infected and HIV-Uninfected Women Living in the Southern United States: A Cross-Sectional Multilevel Analysis

Details

• Alternative Title:
  Sex Transm Infect
• Personal Author:
  Haley, Danielle F. ; Kramer, Michael R. ; Adimora, Adaora A. ; Haardörfer, Regine ; Wingood, Gina M. ; Ludema, Christina ; Rubtsova, Anna ; Hickson, DeMarc A. ; Ross, Zev ; Golub, Elizabeth ; Bolivar, Hector ; Cooper, Hannah LF
• Description:
  Objectives
  
  Neighbourhood characteristics (e.g., high poverty rates) are associated with sexually transmitted infections (STIs) among HIV-uninfected women in the United States (US). However, no multilevel analyses investigating the associations between neighbourhood exposures and STIs have explored these relationships among women living with HIV infection. The objectives of this study were to: 1) examine relationships between neighbourhood characteristics and current STI status, and 2) investigate whether the magnitudes and directions of these relationships varied by HIV status in a predominantly HIV-infected cohort of women living in the southern US.
  
  Methods
  
  This cross-sectional multilevel analysis tests relationships between census tract characteristics and current STI status utilizing data from 737 women enrolled at the Women's Interagency HIV Study's southern sites (530 HIV-infected and 207 HIV-uninfected women). Administrative data (e.g., US Census) described the census tract-level social disorder (e.g., violent crime rate) and social disadvantage (e.g., alcohol outlet density) where women lived. Participant-level data were gathered via survey. Testing positive for a current STI was defined as a laboratory-confirmed diagnosis of chlamydia, gonorrhoea, trichomoniasis, or syphilis. Hierarchical generalized linear models were utilized to determine relationships between tract-level characteristics and current STI status, and to test whether these relationships varied by HIV status.
  
  Results
  
  Eleven percent of participants tested positive for at least one current STI. Greater tract-level social disorder (OR=1.34, 95% CI=0.99, 1.87) and social disadvantage (OR=1.34, 95% CI=0.96, 1.86) were associated with having a current STI. There was no evidence of additive or multiplicative interaction between tract-level characteristics and HIV status.
  
  Conclusions
  
  Findings suggest that neighbourhood characteristics may be associated with current STIs among women living in the South, and that relationships do not vary by HIV status. Future research should establish the temporality of these relationships and explore pathways through which neighbourhoods create vulnerability to STIs.
  
  
• Subjects:
  Adult Article Cross-Sectional Studies Educational Status Female Health Knowledge, Attitudes, Practice HIV HIV Seronegativity HIV Seropositivity Humans Multilevel Analysis Neighbourhood Characteristics Residence Characteristics Sexual Behavior Sexual Health Sexually Transmitted Diseases Sexually Transmitted Infections Social Class Southwestern United States Women Women's Health

  More +
• Source:
  Sex Transm Infect. 93(8):583-589.
• Pubmed ID:
  28270536
• Pubmed Central ID:
  PMC5696110
• Document Type:
  Journal Article
• Funding:
  P30 AI050409/AI/NIAID NIH HHS/United States ; U01 AI103397/AI/NIAID NIH HHS/United States ; K01 HD074726/HD/NICHD NIH HHS/United States ; U01 AI069418/AI/NIAID NIH HHS/United States ; U01 PS003315/PS/NCHHSTP CDC HHS/United States ; UL1 TR000454/TR/NCATS NIH HHS/United States ; UL1 TR002378/TR/NCATS NIH HHS/United States ; U01 AI103401/AI/NIAID NIH HHS/United States ; F31 MH105238/MH/NIMH NIH HHS/United States ; U01 AI103390/AI/NIAID NIH HHS/United States ; UL1 TR000004/TR/NCATS NIH HHS/United States ; U01 AI069477/AI/NIAID NIH HHS/United States ; U01 AI103408/AI/NIAID NIH HHS/United States ; U01 AI042590/AI/NIAID NIH HHS/United States
• Volume:
  93
• Issue:
  8
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:32e23082bfe7040793f01ebfbd4fe5ac46416313a1efbba66591188301419718
• Download URL:
  https://stacks.cdc.gov/view/cdc/49939/cdc_49939_DS1.pdf
• File Type:
  [PDF - 102.29 KB ]