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Utilization of preoperative endoscopic ultrasound for pancreatic adenocarcinoma
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5 2017
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Source: HPB (Oxford). 19(5):465-472
[PDF-695.16 KB]
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Alternative Title:HPB (Oxford)
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Personal Author:
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Description:Background
Endoscopic ultrasound (EUS) is used for pancreatic adenocarcinoma staging and obtaining a tissue diagnosis. The objective was to determine patterns of preoperative EUS and the impact on downstream treatment.
Methods
The Surveillance, Epidemiology, and End Results (SEER) Medicare-linked database was used to identify patients with pancreatic adenocarcinoma. The staging period was the first staging procedure within 6 months of surgery until surgery. Logistic regression was used to determine factors associated with preoperative EUS. The main outcome was EUS in the staging period, with secondary outcomes including number of staging tests and time to surgery.
Results
2782 patients were included, 56% were treated at an academic hospital (n=1563). 1204 patients underwent EUS (43.3%). The factors most associated with receipt of EUS were: earlier year of diagnosis, SEER area, and a NCI or academic hospital (all p < 0.0001). EUS was associated with a longer time to surgery (17.8 days; p < 0.0001), and a higher number of staging tests (40 tests/100 patients; p < 0.0001).
Conclusions
Factors most associated with receipt of EUS are geographic, temporal, and institutional, rather than clinical/disease factors. EUS is associated with a longer time to surgery and more preoperative testing, and additional study is needed to determine if EUS is overused.
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Source:
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Pubmed ID:28237627
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Pubmed Central ID:PMC5695546
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Funding:
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Volume:19
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Issue:5
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