Measurements of Strontium Levels in Human Bone In Vivo Using Portable X-ray Fluorescence (XRF)

Details

• Alternative Title:
  Appl Spectrosc
• Personal Author:
  Specht, Aaron J. ; Mostafaei, Farshad ; Lin, Yanfen ; Xu, Jian ; Nie, Linda H.
• Description:
  Measurement of bone strontium (Sr) is vital to determining the effectiveness of Sr supplementation, which is commonly used for the treatment of osteoporosis. Previous technology uses radioisotope sources and bulky equipment to measure bone Sr. This study demonstrates the effectiveness of portable X-ray fluorescence (XRF) for bone Sr measurement and validates it using data from a population of 238 children. We identified correlations between bone Sr and age in our participants.
• Subjects:
  Article Bone Bone And Bones Calibration Child Child, Preschool Female Humans In Vivo Limit Of Detection Male Phantoms, Imaging Spectrometry, X-Ray Emission Strontium X-ray Fluorescence XRF

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• Source:
  Appl Spectrosc. 71(8):1962-1968
• Pubmed ID:
  28756702
• Pubmed Central ID:
  PMC5617116
• Document Type:
  Journal Article
• Funding:
  P30 ES000002/ES/NIEHS NIH HHSUnited States/ ; R21 ES024700/ES/NIEHS NIH HHSUnited States/ ; R21 OH010044/OH/NIOSH CDC HHSUnited States/ ; R21 OH010700/OH/NIOSH CDC HHSUnited States/
• Volume:
  71
• Issue:
  8
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:d2dd7a13e7a35d147c0c7785a0848ab76cf920817e1c16b4408faebbd49139c3
• Download URL:
  https://stacks.cdc.gov/view/cdc/48438/cdc_48438_DS1.pdf
• File Type:
  [PDF - 870.87 KB ]