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Use of Internet Search Data to Monitor Rotavirus Vaccine Impact in the United States, United Kingdom and Mexico
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2 19 2018
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Source: J Pediatric Infect Dis Soc. 7(1):56-63
[PDF-1.09 MB]
Details:
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Alternative Title:J Pediatric Infect Dis Soc
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Personal Author:
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Description:Background
Prior studies have shown strong correlation between internet search and public health surveillance data. Less is known about how search data responds to public health interventions, such as vaccination, and the consistency of responses in different countries. We aim to study the correlation between rotavirus internet searches and disease activity in the United States (US), United Kingdom (UK) and Mexico, before and after rotavirus vaccine introductions.
Methods
We compared time series of internet searches for “rotavirus” from Google Trends with rotavirus laboratory reports from US and UK, and with acute gastroenteritis hospitalizations from US and Mexico. Using time and location parameters, Google quantifies an Internet Query Share (IQS) to measure relative search volume for specific terms. We analyzed correlation between IQS and laboratory and hospitalization data before and after national vaccine introductions.
Results
There was strong positive correlation between rotavirus IQS and laboratory reports for the US (R2=0.79) and UK (R2=0.60), and between rotavirus IQS and acute gastroenteritis hospitalizations for the US (R2=0.87) and Mexico (R2=0.69), p<.0001 for all correlations. Correlations were stronger in the pre-vaccine period compared to the post-vaccine period. Mean rotavirus IQS decreased after vaccine introduction by 40% (95% CI: 25–55%) in the US and by 70% (95% CI: 55–86%) in Mexico. In the UK, there was a loss of seasonal variation after vaccine introduction.
Conclusions
Rotavirus internet search data trends mirrored national rotavirus laboratory trends in the US and UK, and gastroenteritis hospitalization data in the US and Mexico, with lower correlations following rotavirus vaccine introductions.
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Pubmed ID:28369477
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Pubmed Central ID:PMC5608630
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Funding:
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Volume:7
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Issue:1
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