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Accuracy and Usefulness of Select Methods for Assessing Complete Collection of 24-Hour Urine: A Systematic Review

Supporting Files
File Language:
English


Details

  • Alternative Title:
    J Clin Hypertens (Greenwich)
  • Personal Author:
  • Description:
    Twenty-four-hour urine collection is the recommended method for estimating sodium intake. To investigate the strengths and limitations of methods used to assess completion of 24-hour urine collection, the authors systematically reviewed the literature on the accuracy and usefulness of methods vs para-aminobenzoic acid (PABA) recovery (referent). The percentage of incomplete collections, based on PABA, was 6% to 47% (n=8 studies). The sensitivity and specificity for identifying incomplete collection using creatinine criteria (n=4 studies) was 6% to 63% and 57% to 99.7%, respectively. The most sensitive method for removing incomplete collections was a creatinine index <0.7. In pooled analysis (≥2 studies), mean urine creatinine excretion and volume were higher among participants with complete collection (P<.05); whereas, self-reported collection time did not differ by completion status. Compared with participants with incomplete collection, mean 24-hour sodium excretion was 19.6 mmol higher (n=1781 specimens, 5 studies) in patients with complete collection. Sodium excretion may be underestimated by inclusion of incomplete 24-hour urine collections. None of the current approaches reliably assess completion of 24-hour urine collection.
  • Subjects:
  • Source:
    J Clin Hypertens (Greenwich). 18(5):456-467
  • Pubmed ID:
    26726000
  • Pubmed Central ID:
    PMC5592696
  • Document Type:
  • Funding:
  • Volume:
    18
  • Issue:
    5
  • Collection(s):
  • Main Document Checksum:
    urn:sha256:2b95bfb33e94d7e88968901b082b079c69041e16cc3f3b5e7f16497f7b2a73b8
  • Download URL:
  • File Type:
    Filetype[PDF - 217.77 KB ]
File Language:
English
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