Details:

Alternative Title:
J Chromatogr B Analyt Technol Biomed Life Sci
Personal Author:
Mathias, Patricia I. ; Connor, Thomas H. ; B’Hymer, Clayton ;
Mathias, Patricia I. ; Connor, Thomas H. ; B’Hymer, Clayton ; Less -
Description:
This review describes published high performance liquid chromatography/mass spectrometry (HPLC-MS) methods for the determination of anticancer drugs in human urine as non-invasive tool for monitoring of health care worker exposure to antineoplastic and cytotoxic drugs. HPLC-MS is a sensitive and specific method for analysis of anticancer drugs and their metabolites in biological fluids. In this review, a tabular summary and overview of published HPLC-MS methods are presented, as well as future trends and limitations in this area of research.
Subject:
[+]
Anticancer Drugs
Antineoplastic Agents
Antineoplastic Drug
Article
Biomarkers
Chromatography, High Pressure Liquid
Health Personnel
Humans
Liquid Chromatography
Mass Spectrometry
Occupational Biomonitoring
Occupational Exposure
Urinary Biomarker
Mass Spectrometry

Source:
J Chromatogr B Analyt Technol Biomed Life Sci. 1060:316-324. ;
Pubmed ID:
28654869
Pubmed Central ID:
PMC5585056
Document Type:
Journal Article ;
Funding:
CC999999/Intramural CDC HHS/United States ;
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:f99eb9f589b0c0e1d0aeb669f101bb1f17ffffac56dbd5fe8ec13ea7d859d710
File Type:

Supporting Files

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