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A review of high performance liquid chromatographic-mass spectrometric urinary methods for anticancer drug exposure of healthcare workers
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Jun 19 2017
Source: J Chromatogr B Analyt Technol Biomed Life Sci. 1060:316-324.
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Alternative Title:J Chromatogr B Analyt Technol Biomed Life Sci
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Description:This review describes published high performance liquid chromatography/mass spectrometry (HPLC-MS) methods for the determination of anticancer drugs in human urine as non-invasive tool for monitoring of health care worker exposure to antineoplastic and cytotoxic drugs. HPLC-MS is a sensitive and specific method for analysis of anticancer drugs and their metabolites in biological fluids. In this review, a tabular summary and overview of published HPLC-MS methods are presented, as well as future trends and limitations in this area of research.
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Pubmed ID:28654869
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Pubmed Central ID:PMC5585056
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