Welcome to CDC stacks | Vitamin D and albuminuria in youth with and without type 1 diabetes - 47730 | CDC Public Access
Stacks Logo
Advanced Search
Select up to three search categories and corresponding keywords using the fields to the right. Refer to the Help section for more detailed instructions.
 
 
Help
Clear All Simple Search
Advanced Search
Vitamin D and albuminuria in youth with and without type 1 diabetes
  • Published Date:
    May 29 2017
  • Source:
    Horm Res Paediatr. 87(6):385-395.


Public Access Version Available on: May 29, 2018 information icon
Please check back on the date listed above.
Details:
  • Pubmed ID:
    28554178
  • Pubmed Central ID:
    PMC5568007
  • Description:
    BACKGROUND/AIMS

    In adults, lower Vitamin D has been associated with increased albuminuria. This association has not been extensively studied in youth with or without type 1 diabetes.

    METHODS

    We examined the cross-sectional association between vitamin D and albuminuria (urine albumin/creatinine ratio [ACR] ≥30 mg/g) in 8,789 participants of the National Health and Nutrition Survey 2001–2006 (NHANES), who were 6-19 years old. Further, we examined the association between vitamin D and albuminuria in 938 participants from the SEARCH Nutritional Ancillary Study (SNAS), a longitudinal cohort of youth with type 1 diabetes.

    RESULTS

    In NHANES, 5.3%, 19.5%, and 53.7% had vitamin D levels less than 30, 50 and 80 nmol/L. Albuminuria was present in 12.8% and was more common in younger children, females, non-Hispanic whites, non-obese children, and children with hypertension. After adjustments, there was no association between vitamin D and albuminuria. In SNAS participants with type 1 diabetes, we also found no association between baseline vitamin D and subsequent albuminuria, in unadjusted or adjusted analyses.

    CONCLUSION

    We did not find an association between serum vitamin D and albuminuria in either non-diabetic youth or those with type 1 diabetes. Further research is needed to more fully understand this relationship.

  • Document Type:
  • Collection(s):
  • Funding:
    P30 DK057516/DK/NIDDK NIH HHS/United States
    UC4 DK108173/DK/NIDDK NIH HHS/United States
    U01 DP000247/DP/NCCDPHP CDC HHS/United States
    R01 DK077949/DK/NIDDK NIH HHS/United States
    U18 DP006131/DP/NCCDPHP CDC HHS/United States
    U18 DP002710/DP/NCCDPHP CDC HHS/United States
    U18 DP006134/DP/NCCDPHP CDC HHS/United States
    U18 DP006138/DP/NCCDPHP CDC HHS/United States
    M01 RR000069/RR/NCRR NIH HHS/United States
    UL1 TR000154/TR/NCATS NIH HHS/United States
    U18 DP002714/DP/NCCDPHP CDC HHS/United States
    U01 DP000248/DP/NCCDPHP CDC HHS/United States
    M01 RR000037/RR/NCRR NIH HHS/United States
    U01 DP000244/DP/NCCDPHP CDC HHS/United States
    UL1 RR029882/RR/NCRR NIH HHS/United States
    U18 DP006136/DP/NCCDPHP CDC HHS/United States
    U18 DP002709/DP/NCCDPHP CDC HHS/United States
    U18 DP006133/DP/NCCDPHP CDC HHS/United States
    UL1 TR001425/TR/NCATS NIH HHS/United States
    P30 DK056350/DK/NIDDK NIH HHS/United States
    U18 DP006139/DP/NCCDPHP CDC HHS/United States
    K23 DK089017/DK/NIDDK NIH HHS/United States
    UL1 TR000423/TR/NCATS NIH HHS/United States
    U01 DP000250/DP/NCCDPHP CDC HHS/United States
    U01 DP000246/DP/NCCDPHP CDC HHS/United States
    UL1 TR001450/TR/NCATS NIH HHS/United States
    U01 DP000254/DP/NCCDPHP CDC HHS/United States
    UL1 RR026314/RR/NCRR NIH HHS/United States
    U18 DP002708/DP/NCCDPHP CDC HHS/United States
  • Supporting Files:
    No Additional Files
No Related Documents.
You May Also Like: