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Genome-wide association study to identify variants associated with vaso-occlusive pain in sickle cell anemia
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  1. Association between Baseline Fetal Hemoglobin Levels and Incidence of Severe Vaso-Occlusive Pain Episodes in Children with Sickle Cell Anemia
    Personal Author:
    Bhatnagar, Pallav; Keefer, Jeffrey R.; Casella, James F.; Barron-Casella, Emily A.; Bean, Christopher J.; Hooper, Craig W.; Payne, Amanda B.; Arking, Dan E.; DeBaun, Michael R.;
    Published:
    May 15 2013
    Source:
    Pediatr Blood Cancer. 60(10):E125-E127.
    Description:
    The ameliorating effect of high fetal hemoglobin (HbF) levels on the incidence of pain episodes in sickle cell anemia (SCA) is well-known; however, in children this relationship is less clearly established. We hypothesized that higher HbF levels in c...
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  2. Genome-Wide Meta-Analysis of Systolic Blood Pressure in Children with Sickle Cell Disease
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    Bhatnagar, Pallav; Barron-Casella, Emily; Bean, Christopher J.; Milton, Jacqueline N.; Baldwin, Clinton T.; Steinberg, Martin H.; DeBaun, Michael; Casella, James F.; Arking, Dan E.;
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    Sep 13 2013
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    PLoS One. 2013; 8(9).
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    In pediatric sickle cell disease (SCD) patients, it has been reported that higher systolic blood pressure (SBP) is associated with increased risk of a silent cerebral infarction (SCI). SCI is a major cause of neurologic morbidity in children with SCD...
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  3. Hospital utilization patterns and costs for adult sickle cell patients in Illinois.
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    Woods, K; Karrison, T; Koshy, M; Patel, A; Friedmann, P; Cassel, C;
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    1997 Jan-Feb
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    Public Health Rep. 112(1):44-51
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    To determine population size, demographic characteristics, hospital utilization patterns, the specialties of physicians providing care, and costs for hospitalized adult sickle cell patients in Illinois.|A statewide, administrative dataset for the two...
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  4. The accuracy of hospital ICD-9-CM codes for determining Sickle Cell Disease genotype
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    Snyder, Angela B.; Lane, Peter A.; Zhou, Mei; Paulukonis, Susan T.; Hulihan, Mary M.;
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    Jul 28 2017
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    J Rare Dis Res Treat. 2(4):39-45.
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    Sickle cell disease affects more than 100,000 individuals in the United States, among whom disease severity varies considerably. One factor that influences disease severity is the sickle cell disease genotype. For this reason, clinical prevention and...
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  5. Longitudinal data collection for sickle cell disease in California : history, goals and challenges
    Personal Author:
    Paulukonis, Susan T.; Raider, Faith; Hulihan, Mary M.;
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    Public Health Institute (Calif.). California Rare Disease Surveillance Program.. Public Health Institute (Calif.). California Environmental Health Trackin Program.. National Center on Birth Defects and Developmental Disabilities (Centers for Disease Control and Prevention). Division of Blood Disorders.. Pfizer, Inc.. Biogen, Inc.. CDC Foundation..
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    Sickle cell disease (SCD) is the most common severe genetid disease. It impacts approximately 7,000 people in California and nearly 90,000 in the U.S. And yet remarkably little is known about the population impacted by SCD as a whole. Only recently h...
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