Characteristics of Dysphagia in Infants with Microcephaly Caused by Congenital Zika Virus Infection, Brazil, 2015

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Leal, Mariana C. ; van der Linden, Vanessa ; Bezerra, Thiago P. ; de Valois, Luciana ; Borges, Adriana C.G. ; Antunes, Margarida M.C. ; Brandt, Kátia G. ; Moura, Catharina X. ; Rodrigues, Laura C. ; Ximenes, Coeli R.
• Description:
  We summarize the characteristics of dysphagia in 9 infants in Brazil with microcephaly caused by congenital Zika virus infection. The Schedule for Oral Motor Assessment, fiberoptic endoscopic evaluation of swallowing, and the videofluoroscopic swallowing study were used as noninstrumental and instrumental assessments. All infants had a degree of neurologic damage and showed abnormalities in the oral phase. Of the 9 infants, 8 lacked oral and upper respiratory tract sensitivity, leading to delays in initiation of the pharyngeal phase of swallowing. Those delays, combined with marked oral dysfunction, increased the risk for aspiration of food, particularly liquid foods. Dysphagia resulting from congenital Zika virus syndrome microcephaly can develop in infants >3 months of age and is severe.
• Subjects:
  Deglutition Disorders Female Humans Infant Microcephaly Pregnancy Pregnancy Complications, Infectious Synopsis Zika Virus Infection
• Source:
  Emerg Infect Dis. 23(8):1253-1259.
• Pubmed ID:
  28604336
• Pubmed Central ID:
  PMC5547788
• Document Type:
  Journal Article
• Place as Subject:
  Brazil
• Volume:
  23
• Issue:
  8
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:14a59d3e6e7be8415ddef4ef0d079bcfec94bfe7e9a4c454b8eb7961cf171875
• Download URL:
  https://stacks.cdc.gov/view/cdc/47409/cdc_47409_DS1.pdf
• File Type:
  [PDF - 843.91 KB ]