Factors Associated with Mobility Outcomes in a National Spina Bifida Patient Registry

Details

• Alternative Title:
  Am J Phys Med Rehabil
• Personal Author:
  Dicianno, Brad E. ; Karmarkar, Amol ; Houtrow, Amy ; Crytzer, Theresa M. ; Cushanick, Katelyn M. ; McCoy, Andrew ; Wilson, Pamela ; Chinarian, James ; Neufeld, Jacob ; Smith, Kathryn ; Collins, Diane M.
• Description:
  Objective
  
  To provide descriptive data on ambulatory ability and muscle strength in a large cohort of individuals with spina bifida enrolled in a National Spina Bifida Patient Registry (NSBPR) and to investigate factors associated with ambulatory status.
  
  Design
  
  Cross-sectional analysis of data from a multi-site patient registry
  
  Results
  
  Descriptive analysis of mobility variables for 2604 individuals with spina bifida age 5 and above are presented from 19 sites in the United States. Analysis of a subset of NSBPR data from 380 individuals from three sites accompanied by data from a specialized spina bifida electronic medical record revealed that those with no history of a shunt, lower motor level, and no history of hip or knee contracture release surgery were more likely to be ambulatory at the community level than at the household or wheelchair level.
  
  Conclusion
  
  This study is the first to examine factors associated with ambulatory status in a large sample of individuals with myelomeningocele and non-myelomeningocele subtypes of SB. Results of this study delineate the breadth of strength and functional abilities within the different age groups and subtypes of SB. The results may inform clinicians of the characteristics of those with varying ambulatory abilities.
  
  
• Subjects:
  Adolescent Adult Aged Age Factors Cerebrospinal Fluid Shunts Child Child, Preschool Cohort Studies Cross-Sectional Studies Dependent Ambulation Female Humans Male Middle Aged Mobility Limitation Muscle Strength Outcome Assessment (Health Care) Registries Spinal Dysraphism Wheelchairs Young Adult

  More +
• Source:
  Am J Phys Med Rehabil. 94(12):1015-1025.
• Pubmed ID:
  26488146
• Pubmed Central ID:
  PMC5533185
• Document Type:
  Journal Article
• Funding:
  R24 HD065702/HD/NICHD NIH HHS/United States ; U01 DD001078/DD/NCBDD CDC HHS/United States
• Place as Subject:
  United States
• Volume:
  94
• Issue:
  12
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:6f0d13660a5869472d26229b3e792f18582c49cdcfde0b793eccbcf03d3bda1b
• Download URL:
  https://stacks.cdc.gov/view/cdc/47244/cdc_47244_DS1.pdf
• File Type:
  [PDF - 428.78 KB ]