Cross-lagged panel analysis of depression and behavioral dysfunction in the first year after moderate-to-severe traumatic brain injury

Juengst, Shannon B.; Myrga, John M.; Fann, Jesse R.; Wagner, Amy K.

doi:10.1176/appi.neuropsych.16100217

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Cross-lagged panel analysis of depression and behavioral dysfunction in the first year after moderate-to-severe traumatic brain injury

Published Date:

Mar 15 2017

Publisher's site:

http://dx.doi.org/10.1176/appi.neuropsych.16100217 New Site Icon

Source:

J Neuropsychiatry Clin Neurosci. 29(3):260-266.

[PDF-533.88 KB]

Details:

Personal Authors:

Juengst, Shannon B. ; Myrga, John M. ; Fann, Jesse R. ; Wagner, Amy K. ;

Keywords:

[+]

Pubmed ID:

28294709

Pubmed Central ID:

PMC5533513

Description:

Timely treatment of depression and behavioral dysfunction after moderate-to-severe traumatic brain injury (TBI) could improve health, function, and quality of life. The authors hypothesized that 6-month depression would be the stronger contributor to later depression and behavioral dysfunction in a sample of 88 adults with moderate-to-severe TBI. A structural equation modeling cross-lagged panel analysis, adjusting for all 6-month predictors, revealed that 6-month depression had a stronger relationship to 12-month depression (βstand=0.55, p=0.002) and behavioral dysfunction (βstand=0.41, p=0.004) than did 6-month behavioral dysfunction (βstand=0.17, p=0.270, βstand=0.30, p=0.035). Depression may be in the developmental pathway to behavioral dysfunction, triggering a cycle of reciprocal causality.

Document Type:

Journal Article

Collection(s):

CDC Public Access

Funding:

L30 NS089099/NS/NINDS NIH HHS/United States
U48 DP000041/DP/NCCDPHP CDC HHS/United States

Supporting Files:

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