Cross-lagged panel analysis of depression and behavioral dysfunction in the first year after moderate-to-severe traumatic brain injury

Details

• Alternative Title:
  J Neuropsychiatry Clin Neurosci
• Personal Author:
  Juengst, Shannon B. ; Myrga, John M. ; Fann, Jesse R. ; Wagner, Amy K.
• Description:
  Timely treatment of depression and behavioral dysfunction after moderate-to-severe traumatic brain injury (TBI) could improve health, function, and quality of life. The authors hypothesized that 6-month depression would be the stronger contributor to later depression and behavioral dysfunction in a sample of 88 adults with moderate-to-severe TBI. A structural equation modeling cross-lagged panel analysis, adjusting for all 6-month predictors, revealed that 6-month depression had a stronger relationship to 12-month depression (β|=0.55, p=0.002) and behavioral dysfunction (β|=0.41, p=0.004) than did 6-month behavioral dysfunction (β|=0.17, p=0.270, β|=0.30, p=0.035). Depression may be in the developmental pathway to behavioral dysfunction, triggering a cycle of reciprocal causality.
• Subjects:
  Adult Brain Injuries, Traumatic Cohort Studies Depression Female Humans Male Mental Disorders Psychiatric Status Rating Scales Self Report
• Keywords:
  Behavioral Symptoms Brain Injuries Depression
• Source:
  J Neuropsychiatry Clin Neurosci. 29(3):260-266
• Pubmed ID:
  28294709
• Pubmed Central ID:
  PMC5533513
• Document Type:
  Journal Article
• Funding:
  L30 NS089099/NS/NINDS NIH HHSUnited States/ ; U48 DP000041/DP/NCCDPHP CDC HHSUnited States/
• Volume:
  29
• Issue:
  3
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:953e9d8086335809f097b07b9bb0c0f36d9929273e3d34707456fe4fab0a5e15
• Download URL:
  https://stacks.cdc.gov/view/cdc/47215/cdc_47215_DS1.pdf
• File Type:
  [PDF - 533.88 KB ]