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Cross-lagged panel analysis of depression and behavioral dysfunction in the first year after moderate-to-severe traumatic brain injury
  • Published Date:
    Mar 15 2017
  • Source:
    J Neuropsychiatry Clin Neurosci. 29(3):260-266.


Public Access Version Available on: January 01, 2018 information icon
Please check back on the date listed above.
Details:
  • Pubmed ID:
    28294709
  • Pubmed Central ID:
    PMC5533513
  • Description:
    Timely treatment of depression and behavioral dysfunction after moderate-to-severe traumatic brain injury (TBI) could improve health, function, and quality of life. The authors hypothesized that 6-month depression would be the stronger contributor to later depression and behavioral dysfunction in a sample of 88 adults with moderate-to-severe TBI. A structural equation modeling cross-lagged panel analysis, adjusting for all 6-month predictors, revealed that 6-month depression had a stronger relationship to 12-month depression (βstand=0.55, p=0.002) and behavioral dysfunction (βstand=0.41, p=0.004) than did 6-month behavioral dysfunction (βstand=0.17, p=0.270, βstand=0.30, p=0.035). Depression may be in the developmental pathway to behavioral dysfunction, triggering a cycle of reciprocal causality.

  • Document Type:
  • Collection(s):
  • Funding:
    L30 NS089099/NS/NINDS NIH HHS/United States
    U48 DP000041/DP/NCCDPHP CDC HHS/United States
  • Supporting Files:
    No Additional Files
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