Mild Traumatic Brain Injuries and Risk for Affective and Behavioral Disorders

Details

• Alternative Title:
  Pediatrics
• Personal Author:
  Delmonico, Richard L. ; Tucker, Lue-Yen ; Theodore, Brian R. ; Camicia, Michelle ; Filanosky, Charles ; Haarbauer-Krupa, Juliet
• Description:
  OBJECTIVES:
  
  Recent studies document an association between mild traumatic brain injuries (mTBIs) in children and postinjury psychiatric disorders. However. these studies were subject to limitations in the design, lack of long-term follow-up, and poorly defined psychiatric outcomes. This study determines the incidence and relative risk of postinjury new affective and behavior disorders 4 years after mTBIs.
  
  METHODS:
  
  A cohort study of mTBI cases and matched comparisons within an integrated health care system. The mTBI group included patients ≤17 years of age, diagnosed with mTBI from 2000 to 2014 (N = 18 917). Comparisons included 2 unexposed patients (N = 37 834) per each mTBI-exposed patient, randomly selected and matched for age, sex, race/ethnicity, and date of medical visit (reference date to mTBI injury). Outcomes included a diagnosis of affective or behavioral disorders in the 4 years after mTBI or the reference date.
  
  RESULTS:
  
  Adjusted risks for affective disorders were significantly higher across the first 3 years after injury for the mTBI group, especially during the second year, with a 34% increase in risk. Adjusted risks for behavioral disorders were significant at years 2 and 4, with up to a 37% increase in risk. The age group with the highest risk for postinjury affective and behavioral disorders was 10- to 13-year-old patients.
  
  CONCLUSIONS:
  
  Sustaining an mTBI significantly increased the risks of having a new affective or behavioral disorder up to 4 years after injury. Initial and ongoing screening for affective and behavior disorders following an mTBI can identify persistent conditions that may pose barriers to recovery.
  
  
• Subjects:
  Adolescent Brain Concussion Brain Injuries, Traumatic Child Cohort Studies Female Humans Longitudinal Studies Male Mental Disorders Risk

  More +
• Source:
  Pediatrics. 153(2)
• Pubmed ID:
  38268428
• Pubmed Central ID:
  PMC10983778
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  153
• Issue:
  2
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:5d994082bb5c699683fffcdd82a71d0e2d75c3161c35e10d199d05f9c178b821
• Download URL:
  https://stacks.cdc.gov/view/cdc/153644/cdc_153644_DS1.pdf
• File Type:
  [PDF - 596.98 KB ]