Disseminated Mycobacterium genavense Infection in Patient with Adult-Onset Immunodeficiency

Asakura, Takanori; Namkoong, Ho; Sakagami, Takuro; Hasegawa, Naoki; Ohkusu, Kiyofumi; Nakamura, Akira

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Disseminated Mycobacterium genavense Infection in Patient with Adult-Onset Immunodeficiency

Jul 2017
By Asakura, Takanori ; Namkoong, Ho ; Sakagami, Takuro ; ...
Source: Emerg Infect Dis. 23(7):1208-1210.

[PDF-340.49 KB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Asakura, Takanori ; Namkoong, Ho ; Sakagami, Takuro ; Hasegawa, Naoki ; Ohkusu, Kiyofumi ; ... More +

Asakura, Takanori ; Namkoong, Ho ; Sakagami, Takuro ; Hasegawa, Naoki ; Ohkusu, Kiyofumi ; Nakamura, Akira Less -
Description:

We report a case of disseminated Mycobacterium genavense infection resulting from neutralizing anti-interferon-γ autoantibodies in the patient. We identified M. genavense targeting the hsp65 gene in an aspiration specimen of the lymph node. Adult-onset immunodeficiency caused by neutralizing anti-interferon-γ autoantibodies, in addition to HIV infection, can lead to disseminated nontuberculous mycobacterial infection.
Subjects:

[+]

Aged Autoantibodies Biopsy Cd4-Cd8 Ratio Humans Immunocompromised Host Interferon-Gamma Lymphadenopathy Male Mycobacterium Infections, Nontuberculous Nontuberculous Mycobacteria Positron Emission Tomography Computed Tomography Tomography, X-Ray Computed
Source:

Emerg Infect Dis. 23(7):1208-1210.
Pubmed ID:

28628454
Pubmed Central ID:

PMC5512497
Document Type:

Journal Article
Volume:

23
Issue:

7
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:9e2620f4dfdb2c70a8edc365834a0013c49aa8d0e09f054dfee72f10d57587af
Download URL:

https://stacks.cdc.gov/view/cdc/46757/cdc_46757_DS1.pdf
File Type:

	16-1677-Techapp-s1.pdf	pdf
	16-1677.nxml	bin

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