Disseminated Mycobacterium genavense Infection in Patient with Adult-Onset Immunodeficiency

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Asakura, Takanori ; Namkoong, Ho ; Sakagami, Takuro ; Hasegawa, Naoki ; Ohkusu, Kiyofumi ; Nakamura, Akira
• Description:
  We report a case of disseminated Mycobacterium genavense infection resulting from neutralizing anti-interferon-γ autoantibodies in the patient. We identified M. genavense targeting the hsp65 gene in an aspiration specimen of the lymph node. Adult-onset immunodeficiency caused by neutralizing anti-interferon-γ autoantibodies, in addition to HIV infection, can lead to disseminated nontuberculous mycobacterial infection.
• Subjects:
  Aged Autoantibodies Biopsy Cd4-Cd8 Ratio Humans Immunocompromised Host Interferon-Gamma Lymphadenopathy Male Mycobacterium Infections, Nontuberculous Nontuberculous Mycobacteria Positron Emission Tomography Computed Tomography Tomography, X-Ray Computed

  More +
• Source:
  Emerg Infect Dis. 23(7):1208-1210.
• Pubmed ID:
  28628454
• Pubmed Central ID:
  PMC5512497
• Document Type:
  Journal Article
• Volume:
  23
• Issue:
  7
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:9e2620f4dfdb2c70a8edc365834a0013c49aa8d0e09f054dfee72f10d57587af
• Download URL:
  https://stacks.cdc.gov/view/cdc/46757/cdc_46757_DS1.pdf
• File Type:
  [PDF - 340.49 KB ]