Breast cancer in Asian Americans in California, 1988–2013: increasing incidence trends and recent data on breast cancer subtypes

Details

• Alternative Title:
  Breast Cancer Res Treat
• Personal Author:
  Gomez, Scarlett Lin ; Von Behren, Julie ; McKinley, Meg ; Clarke, Christina A. ; Shariff-Marco, Salma ; Cheng, Iona ; Reynolds, Peggy ; Glaser, Sally L.
• Description:
  Purpose
  
  In contrast to other US racial/ethnic groups, Asian Americans (AA) have experienced steadily increasing breast cancer rates in recent decades. To better understand potential contributors to this increase, we examined incidence trends by age and stage among women from seven AA ethnic groups in California from 1988 through 2013, and incidence patterns by subtype and age at diagnosis for the years 2009 through 2013.
  
  Methods
  
  Joinpoint regression was applied to California Cancer Registry data to calculate annual percentage change (APC) for incidence trends. Incidence rate ratios were used to compare rates for AA ethnic groups relative to non-Hispanic whites (NHW).
  
  Results
  
  All AA groups except Japanese experienced incidence increases, with the largest among Koreans in 1988–2006 (APC: 4.7, 95% CI: 3.8, 5.7) and Southeast Asians in 1988–2013 (APC: 2.5, 95% CI: 0.8, 4.2). Among women younger than age 50, large increases occurred for Vietnamese and other Southeast Asians; among women over age 50, increasing trends occurred in all AA ethnic groups. Rates increased for distant stage disease among Filipinas (2.2% per year, 95% CI: 0.4, 3.9). Compared to NHW, Filipinas and older Vietnamese had higher incidence rates of some HER2+ subtypes.
  
  Conclusions
  
  Breast cancer incidence rates have risen rapidly among California AA, with the greatest increases in Koreans and Southeast Asians. Culturally-tailored efforts to increase awareness of and attention to breast cancer risk factors are needed. Given the relatively higher rates of HER2-overexpressing subtypes in some AA ethnicities, research including these groups and their potentially unique exposures may help elucidate disease etiology.
  
  
• Subjects:
  Adult Aged Asian Breast Neoplasms Female Humans Middle Aged Receptor, ErbB-2 Registries White People
• Source:
  Breast Cancer Res Treat. 164(1):139-147
• Pubmed ID:
  28365834
• Pubmed Central ID:
  PMC5484636
• Document Type:
  Journal Article
• Funding:
  HHSN261201000140C/CA/NCI NIH HHSUnited States/ ; HHSN261201000035C/CA/NCI NIH HHSUnited States/ ; HHSN261201000036C/CA/NCI NIH HHSUnited States/ ; HHSN261201000035I/CA/NCI NIH HHSUnited States/ ; HHSN261201000034C/CA/NCI NIH HHSUnited States/ ; U58 DP003862/DP/NCCDPHP CDC HHSUnited States/ ; P30 CA124435/CA/NCI NIH HHSUnited States/
• Name as Subject:
  SEER Program ; SEER Program
• Place as Subject:
  California
• Volume:
  164
• Issue:
  1
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:fcaa94167029ced8dff965fd074c21a0445600c79a31aa9659c7b4570622c096
• Download URL:
  https://stacks.cdc.gov/view/cdc/46652/cdc_46652_DS1.pdf
• File Type:
  [PDF - 901.98 KB ]