An inter- laboratory proficiency testing exercise for rabies diagnosis in Latin America and the Caribbean

Clavijo, Alfonso; Freire de Carvalho, Mary H.; Orciari, Lillian A.; Velasco-Villa, Andres; Ellison, James A.; Greenberg, Lauren; Yager, Pamela A.; Green, Douglas B.; Vigilato, Marco A.; Cosivi, Ottorino; Del Rio-Vilas, Victor J.

doi:10.1371/journal.pntd.0005427

i

An inter- laboratory proficiency testing exercise for rabies diagnosis in Latin America and the Caribbean

Supporting Files Public Domain

Apr 03 2017
By Clavijo, Alfonso ; Freire de Carvalho, Mary H. ; Orciari, Lillian A. ; ...

File Language:

English

Details

Alternative Title:

PLoS Negl Trop Dis
Personal Author:

Clavijo, Alfonso ; Freire de Carvalho, Mary H. ; Orciari, Lillian A. ; Velasco-Villa, Andres ; Ellison, James A. ; Greenberg, Lauren ; Yager, Pamela A. ; Green, Douglas B. ; Vigilato, Marco A. ; Cosivi, Ottorino ; Del Rio-Vilas, Victor J.
Description:

The direct fluorescent antibody test (DFA), is performed in all rabies reference laboratories across Latin America and the Caribbean (LAC). Despite DFA being a critical capacity in the control of rabies, there is not a standardized protocol in the region. We describe the results of the first inter-laboratory proficiency exercise of national rabies laboratories in LAC countries as part of the regional efforts towards dog-maintained rabies elimination in the American region. Twenty three laboratories affiliated to the Ministries of Health and Ministries of Agriculture participated in this exercise. In addition, the laboratories completed an online questionnaire to assess laboratory practices. Answers to the online questionnaire indicated large variability in the laboratories throughput, equipment used, protocols availability, quality control standards and biosafety requirements. Our results will inform actions to improve and harmonize laboratory rabies capacities across LAC in support for the regional efforts towards elimination of dog-maintained rabies.
Subjects:

Brain Disease Eradication Dog Diseases Dogs Fluorescent Antibody Technique, Direct Humans International Cooperation Internet Laboratory Proficiency Testing Public Health Quality Control Rabies Rabies Virus Sensitivity And Specificity Surveys And Questionnaires
Source:

PLoS Negl Trop Dis. 11(4).
Pubmed ID:

28369139
Pubmed Central ID:

PMC5391118
Document Type:

Journal Article
Place as Subject:

Caribbean Region ; Latin America
Volume:

11
Issue:

4
Collection(s):

CDC Public Access
Main Document Checksum:

urn:sha256:c4b680f1f270990eca797209dcf1daf6946c2d14a1674b30a178957ba7fc9ad9
Download URL:

https://stacks.cdc.gov/view/cdc/45716/cdc_45716_DS1.pdf
File Type:

[PDF - 918.57 KB ]

File Language:

English

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