Multidrug-resistant tuberculosis patients’ views of interventions to reduce treatment loss to follow-up

Details

• Alternative Title:
  Int J Tuberc Lung Dis
• Personal Author:
  Tupasi, T. ; Garfin, A. M. C. G. ; Mangan, J. M. ; Orillaza-Chi, R. ; Naval, L. C. ; Balane, G. I. ; Basilio, R. ; Golubkov, A. ; Joson, E. S. ; Lew, W-J. ; Lofranco, V. ; Mantala, M. ; Pancho, S. ; Sarol, J. N. ; Blumberg, A. ; Burt, D. ; Kurbatova, E. V.
• Description:
  SETTING
  
  Patients who initiated treatment for multi-drug-resistant tuberculosis (MDR-TB) at 15 Programmatic Management of Drug-resistant Tuberculosis (PMDT) health facilities in the Philippines between July and December 2012.
  
  OBJECTIVES
  
  To describe patients’ views of current interventions, and suggest changes likely to reduce MDR-TB loss to follow-up.
  
  METHODS
  
  In-depth interviews were conducted between April and July 2014 with MDR-TB patients who were undergoing treatment, had finished treatment at the time of the interview (controls), or had been lost to follow-up (LTFU). Responses were thematically analyzed.
  
  RESULTS
  
  Interviews were conducted with 182 patients who were undergoing or had completed treatment and 91 LTFU patients. Views and suggestions could be thematically categorized as approaches to facilitate adherence or address barriers to adherence. The top themes were the need for transportation assistance or improvements to the current transportation assistance program, food assistance, and difficulties patients encountered related to their medications. These themes were addressed by respectively 63%, 60%, and 32% of the participants.
  
  CONCLUSIONS
  
  A more patient-centered approach is needed to improve MDR-TB treatment adherence. Programs should strive to provide assistance that considers patient preferences, is adequate to cover actual costs or needs, and is delivered in a timely, uninterrupted manner.
  
  
• Subjects:
  Adult Antitubercular Agents Case-Control Studies Female Humans Lost To Follow-Up Male Middle Aged Patient Preference Philippines Retrospective Studies Socioeconomic Factors Tuberculosis, Multidrug-Resistant Young Adult

  More +
• Keywords:
  Adherence Enablers Incentives Patient-centered Qualitative Study
• Source:
  Int J Tuberc Lung Dis. 21(1):23-31
• Pubmed ID:
  28157461
• Pubmed Central ID:
  PMC5427639
• Document Type:
  Journal Article
• Funding:
  001/WHO_/World Health OrganizationInternational/ ; CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  21
• Issue:
  1
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:7d5fdbd7a02fbc1e0c1f815105b66df6a50cba3efb2e8035c68d83c758e48477
• Download URL:
  https://stacks.cdc.gov/view/cdc/45681/cdc_45681_DS1.pdf
• File Type:
  [PDF - 312.28 KB ]