Multidrug-resistant tuberculosis patients lost to follow-up: self-reported readiness to restart treatment

Details

• Alternative Title:
  Int J Tuberc Lung Dis
• Personal Author:
  Mangan, J. M. ; Tupasi, T. E. ; Garfin, A. M. C. G. ; Lofranco, V. ; Orillaza-Chi, R. ; Basilio, R. ; Naval, L. C. ; Balane, G. I. ; Joson, E. S. ; Burt, D. ; Lew, W-J. ; Mantala, M. ; Pancho, S. ; Sarol, J. N. ; Golubkov, A. ; Kurbatova, E. V.
• Description:
  SETTING
  
  Multidrug-resistant tuberculosis (MDR-TB) patients lost to follow-up (LTFU) from Programmatic Management of Drug-resistant Tuberculosis facilities in the Philippines.
  
  OBJECTIVES
  
  To gain insight into patients’ readiness to return to treatment.
  
  METHODS
  
  MDR-TB patients who initiated treatment and were categorized as LTFU were identified using TB registers, contacted, and asked to consent to an interview and medical record review. At the conclusion of the interview, patients’ readiness to restart treatment was assessed and examined in relation to demographic, clinical, and interview data. Odds ratios were calculated.
  
  RESULTS
  
  When asked if they would consider restarting MDR-TB treatment, 3% of the 89 participating patients reported that they had already restarted, 34% indicated that they wanted to restart, 33% had not considered restarting, 28% were undecided, and 2% had decided against restarting. Patients who wanted to restart treatment were more likely to report having borrowed money for TB-related expenses (OR 5.97, 95%CI 1.27– 28.18), and were less likely to report being self-employed (OR 0.08, 95%CI 0.01–0.67), or perceive themselves at low or no risk for TB relapse (OR 0.30, 95%CI 0.08–0.96) than patients who did not indicate an interest in restarting treatment.
  
  CONCLUSIONS
  
  Efforts to re-engage LTFU patients in care should consider financial barriers, knowledge gaps, and personal adherence challenges in patients.
  
  
• Subjects:
  Adolescent Adult Aged Antitubercular Agents Article Case-Control Studies Cohort Studies Female Health Behavior Humans Lost To Follow-Up Male Medication Adherence Middle Aged Patient Decision Patient Education Philippines Readiness Self Report Socioeconomic Factors Stages Of Change Tuberculosis, Multidrug-Resistant Young Adult

  More +
• Source:
  Int J Tuberc Lung Dis. 20(9):1205-1211
• Pubmed ID:
  27510247
• Pubmed Central ID:
  PMC5427632
• Document Type:
  Journal Article
• Funding:
  001/World Health Organization/International ; CC999999/Intramural CDC HHS/United States
• Volume:
  20
• Issue:
  9
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:890e51fdc61e1ae256caf69c80cb8773a149ddeb106d897ee2eb5a7fac89c90f
• Download URL:
  https://stacks.cdc.gov/view/cdc/45680/cdc_45680_DS1.pdf
• File Type:
  [PDF - 661.49 KB ]