Details:

Alternative Title:
Environ Health Perspect
Personal Author:
Hatcher, Sarah M. ; Rhodes, Sarah M. ; Stewart, Jill R. ; Silbergeld, Ellen ; Pisanic, Nora ; ... More +
Hatcher, Sarah M. ; Rhodes, Sarah M. ; Stewart, Jill R. ; Silbergeld, Ellen ; Pisanic, Nora ; Larsen, Jesper ; Jiang, Sharon ; Krosche, Amanda ; Hall, Devon ; Carroll, Karen C. ; Heaney, Christopher D. Less -
Description:
Background:

Antibiotic use in industrial hog operations (IHOs) can support the emergence of antibiotic-resistant (ABR) Staphylococcus aureus. The extent of ABR S. aureus exposure in IHO workers and children living in their households remains unclear.

Objective:

We investigated ABR S. aureus nasal carriage prevalence among adults with versus without occupational exposure to IHOs and among children living in their households.

Methods:

In total, 198 IHO worker–child household pairs and 202 community referent (CR) adult–child household pairs completed a questionnaire and provided a nasal swab which was analyzed for S. aureus, methicillin-resistant S. aureus (MRSA), multidrug-resistant S. aureus (MDRSA), absence of scn (putative marker of livestock association), and spa type.

Results:

S. aureus nasal carriage prevalence was higher among IHO (53%) compared with CR (31%) adults [adjusted prevalence ratio (aPR): 1.40; 95% confidence interval (CI): 1.07, 1.83], but MRSA nasal carriage prevalence was uncommon (2–3%) in IHO and CR adults. MDRSA nasal carriage prevalence was similar among IHO workers and CR adults (12% vs. 8%; aPR: 1.14; 95% CI: 0.56, 2.29). Nasal carriage prevalence was higher among IHO compared with CR children for S. aureus (49% vs. 31%; aPR: 1.50; 95% CI: 1.13, 1.99), MRSA (14% vs. 6%; aPR: 2.37; 95% CI: 1.14, 4.92), and MDRSA (23% vs. 8%; aPR: 2.64; 95% CI: 1.47, 4.75). We also found suggestive evidence of a higher prevalence of S. aureus, MRSA, and MDRSA among children living with an IHO worker who did versus did not report taking personal protective equipment (PPE) home from the IHO. Livestock-associated S. aureus nasal carriage predominated among IHO workers.

Conclusion:

Our findings support the importance of further research on the prevalence and potential sources of exposure to ABR S. aureus among children living with IHO workers.

Citation:

Hatcher SM, Rhodes SM, Stewart JR, Silbergeld E, Pisanic N, Larsen J, Jiang S, Krosche A, Hall D, Carroll KC, Heaney CD. 2017. The prevalence of antibiotic-resistant Staphylococcus aureus nasal carriage among industrial hog operation workers, community residents, and children living in their households: North Carolina, USA. Environ Health Perspect 125:560–569; http://dx.doi.org/10.1289/EHP35


Subject:
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Research

Source:
Environ Health Perspect. 125(4):560-569.
Pubmed ID:
28362266
Pubmed Central ID:
PMC5381988
Document Type:
Journal Article
Funding:
K01 OH010193/OH/NIOSH CDC HHS/United States ; R01 AI101371/AI/NIAID NIH HHS/United States ; T32 ES007018/ES/NIEHS NIH HHS/United States ; T32 ES007141/ES/NIEHS NIH HHS/United States
K01 OH010193/OH/NIOSH CDC HHS/United States ; R01 AI101371/AI/NIAID NIH HHS/United States ; T32 ES007018/ES/NIEHS NIH HHS/United States ; T32 ES007141/ES/NIEHS NIH HHS/United States Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:e9495e048dc3c7fc89b4a706d29340b2f67542f33904cd6505464f242a725e8c
File Type:

Supporting Files

• 	EHP35.nxml	bin
  	EHP35.s001.acco.pdf	pdf
  	EHP35.s002.acco.zip	zip

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