Successful Treatment of Human Plague with Oral Ciprofloxacin

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Apangu, Titus ; Griffith, Kevin ; Abaru, Janet ; Candini, Gordian ; Apio, Harriet ; Okoth, Felix ; Okello, Robert ; Kaggwa, John ; Acayo, Sarah ; Ezama, Geoffrey ; Yockey, Brook ; Sexton, Christopher ; Schriefer, Martin ; Mbidde, Edward Katongole ; Mead, Paul
• Description:
  The US Food and Drug Administration recently approved ciprofloxacin for treatment of plague (Yersina pestis infection) based on animal studies. Published evidence of efficacy in humans is sparse. We report 5 cases of culture-confirmed human plague treated successfully with oral ciprofloxacin, including 1 case of pneumonic plague.
• Subjects:
  Adolescent Adult Anti-Bacterial Agents Child Ciprofloxacin Female Humans Male Middle Aged Plague
• Source:
  Emerg Infect Dis. 23(3):553-555.
• Pubmed ID:
  28125398
• Pubmed Central ID:
  PMC5382724
• Document Type:
  Letter
• Place as Subject:
  Uganda
• Volume:
  23
• Issue:
  3
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:6b78cb8eec51ecc0c5cc2f6271e013b8b43df2a892ae0a86a6e6e352cb9768e7
• Download URL:
  https://stacks.cdc.gov/view/cdc/44935/cdc_44935_DS1.pdf
• File Type:
  [PDF - 644.52 KB ]