Details:

Alternative Title:
Breast Cancer Res Treat
Personal Author:
Hawley, Sarah T. ; Janz, Nancy K. ; Griffith, Kent A. ; Jagsi, Reshma ; Friese, Christopher R. ; ... More +
Hawley, Sarah T. ; Janz, Nancy K. ; Griffith, Kent A. ; Jagsi, Reshma ; Friese, Christopher R. ; Kurian, Allison W. ; Hamilton, Ann S. ; Ward, Kevin C. ; Morrow, Monica ; Wallner, Lauren P. ; Katz, Steven J. ; Less -
Description:
Purpose Little is known about different ways of assessing risk of distant recurrence following cancer treatment (e.g., numeric or descriptive). We sought to evaluate the association between overestimation of risk of distant recurrence of breast cancer and key patient reported outcomes, including quality of life and worry. Methods We surveyed a weighted random sample of newly diagnosed patients with early-stage breast cancer identified through SEER registries of Los Angeles & Georgia (2013-14) ∼2 months after surgery (N=2578, RR=71%). Actual 10-year risk of distant recurrence after treatment was based on clinical factors for women with DCIS & low risk invasive cancer (Stg 1A, ER+HER2-, Gr 1-2). Women reported perceptions of their risk numerically (0 – 100%), with values ≥10% for DCIS & ≥20% for invasive considered overestimates. Perceptions of “moderate, high or very high” risk were considered descriptive overestimates. In our analytic sample (N=927), we assessed factors correlated with both types of overestimation and report multivariable associations between overestimation and QoL (PROMIS physical & mental health) and frequent worry. Results 30.4% of women substantially overestimated their risk of distant recurrence numerically and 14.7% descriptively. Few factors other than family history were significantly associated with either type of overestimation. Both types of overestimation were significantly associated with frequent worry, and lower QoL. Conclusions Ensuring understanding of systemic recurrence risk, particularly among patients with favorable prognosis, is important. Better risk communication by clinicians may translate to better risk comprehension among patients and to improvements in QoL.
Subject:
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Adult
Aged
Aged, 80 And Over
Anxiety
Article
Breast Cancer
Breast Neoplasms
Female
Humans
Middle Aged
Neoplasm Staging
Perception
Population Surveillance
Quality Of Life
Recurrence
Risk
Risk Factors
SEER Program
Quality Of Life
Risk

Source:
Breast Cancer Res Treat. 161(3):557-565. ;
Pubmed ID:
28004220
Pubmed Central ID:
PMC5310669
Document Type:
Journal Article ;
Funding:
HHSN261201000035C/PC,CA/None/None ; HHSN261201000140C/CA/NCI NIH HHS/United States ; P30 CA046592/CA/NCI NIH HHS/United States ; P01 CA163233/CA/NCI NIH HHS/United States ; U58 DP003875/DP/NCCDPHP CDC HHS/United States ; ... More +
HHSN261201000035C/PC,CA/None/None ; HHSN261201000140C/CA/NCI NIH HHS/United States ; P30 CA046592/CA/NCI NIH HHS/United States ; P01 CA163233/CA/NCI NIH HHS/United States ; U58 DP003875/DP/NCCDPHP CDC HHS/United States ; HHSN261201300015C/RC/CCR NIH HHS/United States ; HHSN261201000035I/CA/NCI NIH HHS/United States ; HHSN261201000034C/CA/NCI NIH HHS/United States ; U58 DP003862/DP/NCCDPHP CDC HHS/United States ; U01 CA197282/CA/NCI NIH HHS/United States ; Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:72b0d2fb246e6b6c65f10784dea78bb142e1b1432b0e260708672325b16f7582
File Type:

Supporting Files

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