Recurrence Risk Perception and Quality of Life Following Treatment of Breast Cancer

Details

• Alternative Title:
  Breast Cancer Res Treat
• Personal Author:
  Hawley, Sarah T. ; Janz, Nancy K. ; Griffith, Kent A. ; Jagsi, Reshma ; Friese, Christopher R. ; Kurian, Allison W. ; Hamilton, Ann S. ; Ward, Kevin C. ; Morrow, Monica ; Wallner, Lauren P. ; Katz, Steven J.
• Description:
  Purpose
  
  Little is known about different ways of assessing risk of distant recurrence following cancer treatment (e.g., numeric or descriptive). We sought to evaluate the association between overestimation of risk of distant recurrence of breast cancer and key patient reported outcomes, including quality of life and worry.
  
  Methods
  
  We surveyed a weighted random sample of newly diagnosed patients with early-stage breast cancer identified through SEER registries of Los Angeles & Georgia (2013-14) ∼2 months after surgery (N=2578, RR=71%). Actual 10-year risk of distant recurrence after treatment was based on clinical factors for women with DCIS & low risk invasive cancer (Stg 1A, ER+HER2-, Gr 1-2). Women reported perceptions of their risk numerically (0 – 100%), with values ≥10% for DCIS & ≥20% for invasive considered overestimates. Perceptions of “moderate, high or very high” risk were considered descriptive overestimates. In our analytic sample (N=927), we assessed factors correlated with both types of overestimation and report multivariable associations between overestimation and QoL (PROMIS physical & mental health) and frequent worry.
  
  Results
  
  30.4% of women substantially overestimated their risk of distant recurrence numerically and 14.7% descriptively. Few factors other than family history were significantly associated with either type of overestimation. Both types of overestimation were significantly associated with frequent worry, and lower QoL.
  
  Conclusions
  
  Ensuring understanding of systemic recurrence risk, particularly among patients with favorable prognosis, is important. Better risk communication by clinicians may translate to better risk comprehension among patients and to improvements in QoL.
  
  
• Subjects:
  Adult Aged Aged, 80 And Over Anxiety Breast Neoplasms Female Humans Middle Aged Neoplasm Staging Perception Population Surveillance Quality Of Life Recurrence Risk Risk Factors SEER Program

  More +
• Source:
  Breast Cancer Res Treat. 161(3):557-565.
• Pubmed ID:
  28004220
• Pubmed Central ID:
  PMC5310669
• Document Type:
  Journal Article
• Funding:
  HHSN261201000035C/PC,CA/None/None ; HHSN261201000140C/CA/NCI NIH HHS/United States ; P30 CA046592/CA/NCI NIH HHS/United States ; P01 CA163233/CA/NCI NIH HHS/United States ; U58 DP003875/DP/NCCDPHP CDC HHS/United States ; HHSN261201300015C/RC/CCR NIH HHS/United States ; HHSN261201000035I/CA/NCI NIH HHS/United States ; HHSN261201000034C/CA/NCI NIH HHS/United States ; U58 DP003862/DP/NCCDPHP CDC HHS/United States ; U01 CA197282/CA/NCI NIH HHS/United States
• Volume:
  161
• Issue:
  3
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:72b0d2fb246e6b6c65f10784dea78bb142e1b1432b0e260708672325b16f7582
• Download URL:
  https://stacks.cdc.gov/view/cdc/44258/cdc_44258_DS1.pdf
• File Type:
  [PDF - 466.32 KB ]