Details:

Alternative Title:
PLoS One
Publisher's site:
http://dx.doi.org/10.1371/journal.pone.0168371
Personal Author:
Wangroongsarb, Piyaporn; Hwang, Jimee; Thwing, Julie; Karuchit, Samart; Kumpetch, Suthon; ... More +
Wangroongsarb, Piyaporn; Hwang, Jimee; Thwing, Julie; Karuchit, Samart; Kumpetch, Suthon; Rand, Alison; Drakeley, Chris; MacArthur, John R.; Kachur, S. Patrick; Satimai, Wichai; Meek, Sylvia; Sintasath, David M.; Less -
Description:
Background Ranong Province in southern Thailand is one of the primary entry points for migrants entering Thailand from Myanmar, and borders Kawthaung Township in Myanmar where artemisinin resistance in malaria parasites has been detected. Areas of high population movement could increase the risk of spread of artemisinin resistance in this region and beyond. Methods A respondent-driven sampling (RDS) methodology was used to compare migrant populations coming from Myanmar in urban (Site 1) vs. rural (Site 2) settings in Ranong, Thailand. The RDS methodology collected information on knowledge, attitudes, and practices for malaria, travel and occupational histories, as well as social network size and structure. Individuals enrolled were screened for malaria by microscopy, Real Time-PCR, and serology. Results A total of 619 participants were recruited in Ranong City and 623 participants in Kraburi, a rural sub-district. By PCR, a total of 14 (1.1%) samples were positive (2 P. falciparum in Site 1; 10 P. vivax, 1 Pf, and 1 P. malariae in Site 2). PCR analysis demonstrated an overall weighted prevalence of 0.5% (95% CI, 0–1.3%) in the urban site and 1.0% (95% CI, 0.5–1.7%) in the rural site for all parasite species. PCR positivity did not correlate with serological positivity; however, as expected there was a strong association between antibody prevalence and both age and exposure. Access to long-lasting insecticidal treated nets remains low despite relatively high reported traditional net use among these populations. Conclusions The low malaria prevalence, relatively smaller networks among migrants in rural settings, and limited frequency of travel to and from other areas of malaria transmission in Myanmar, suggest that the risk for the spread of artemisinin resistance from this area may be limited in these networks currently but may have implications for regional malaria elimination efforts.
Subject:
[+]
Adult
Aged
Antimalarials
Artemisinins
Drug Resistance
Female
Health Behavior
Health Knowledge, Attitudes, Practice
Humans
Malaria
Male
Middle Aged
Occupational Exposure
Risk Assessment
Surveys And Questionnaires`
Transients And Migrants
Young Adult

Source:
PLoS One. 11(12).;
Pubmed ID:
28033322
Pubmed Central ID:
PMC5199010
Document Type:
Journal Article;
Place as Subject:
Thailand;
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:945ecc67c79d0153c588e7250eed950989fe11a6706f927282208cd63485e4dc
File Type:

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