Group B Streptococcal Toxic Shock Syndrome and covR/S Mutations Revisited

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Sendi, Parham ; el Hay, Muad Abd ; Brandt, Claudia M. ; Spellerberg, Barbara
• Description:
  Gene mutations in the virulence regulator CovR/S of group A Streptococcus play a substantial role in the pathogenesis of streptococcal toxic shock syndrome. We screened 25 group B Streptococcus (GBS) isolates obtained from patients with streptococcal toxic shock syndrome and found only 1 GBS clone harboring this kind of mutation.
• Subjects:
  Adult Aged Aged, 80 And Over Bacterial Proteins Female Gene Expression Regulation, Bacterial Humans Infant, Newborn Male Middle Aged Multilocus Sequence Typing Mutation Repressor Proteins Serotyping Shock, Septic Streptococcal Infections Streptococcus Agalactiae Survival Analysis Virulence Virulence Factors

  More +
• Source:
  Emerg Infect Dis. 23(1):150-152.
• Pubmed ID:
  27983484
• Pubmed Central ID:
  PMC5176209
• Document Type:
  Letter
• Volume:
  23
• Issue:
  1
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:6be3d3e31c93923acd37fd267949422f68144d1c88b6d0031a6bc5351d9b5cb3
• Download URL:
  https://stacks.cdc.gov/view/cdc/43533/cdc_43533_DS1.pdf
• File Type:
  [PDF - 306.53 KB ]