Genetically Different Highly Pathogenic Avian Influenza A(H5N1) Viruses in West Africa, 2015

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Tassoni, Luca ; Fusaro, Alice ; Milani, Adelaide ; Lemey, Philippe ; Awuni, Joseph Adongo ; Sedor, Victoria Bernice ; Dogbey, Otilia ; Commey, Abraham Nii Okai ; Meseko, Clement ; Joannis, Tony ; Minoungou, Germaine L. ; Ouattara, Lassina ; Haido, Abdoul Malick ; Cisse-Aman, Diarra ; Couacy-Hymann, Emmanuel ; Dauphin, Gwenaelle ; Cattoli, Giovanni ; Monne, Isabella
• Description:
  To trace the evolution of highly pathogenic influenza A(H5N1) virus in West Africa, we sequenced genomes of 43 viruses collected during 2015 from poultry and wild birds in 5 countries. We found 2 co-circulating genetic groups within clade 2.3.2.1c. Mutations that may increase adaptation to mammals raise concern over possible risk for humans.
• Subjects:
  Animals Genetic Variation Genome, Viral Hemagglutinin Glycoproteins, Influenza Virus Humans Influenza A Virus, H5N1 Subtype Influenza In Birds Mutation Phylogeny Poultry Virulence Whole Genome Sequencing

  More +
• Source:
  Emerg Infect Dis. 22(12):2132-2136.
• Pubmed ID:
  27389972
• Pubmed Central ID:
  PMC5189143
• Document Type:
  Journal Article
• Place as Subject:
  Africa, Western
• Location:
  Africa
• Volume:
  22
• Issue:
  12
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:2def53d054e1277e4879b84958e670e55a5307d1a1a7ac32b0a371bf8bcfac7b
• Download URL:
  https://stacks.cdc.gov/view/cdc/43436/cdc_43436_DS1.pdf
• File Type:
  [PDF - 2.24 MB ]