Zika Virus Infection Associated With Severe Thrombocytopenia

Details

• Alternative Title:
  Clin Infect Dis
• Personal Author:
  Sharp, Tyler M. ; Muñoz-Jordán, Jorge ; Perez-Padilla, Janice ; Bello-Pagán, Melissa I. ; Rivera, Aidsa ; Pastula, Daniel M. ; Salinas, Jorge L. ; Martínez Mendez, Jose H. ; Méndez, Mónica ; Powers, Ann M. ; Waterman, Stephen ; Rivera-García, Brenda
• Description:
  We report two patients that developed severe thrombocytopenia after Zika virus (ZIKV) infection. The first patient had 1000 platelets/μL and died after multiple hemorrhages. The second patient had 2000 platelets/μL, had melena and ecchymoses, and recovered after receiving intravenous immunoglobulin. ZIKV may be associated with immune-mediated severe thrombocytopenia.
• Subjects:
  Adult Aged Humans Immunoglobulins, Intravenous Male Thrombocytopenia Treatment Outcome Zika Virus Infection
• Keywords:
  Fatal Puerto Rico Thrombocytopenia Zika Virus
• Source:
  Clin Infect Dis. 63(9):1198-1201
• Pubmed ID:
  27418575
• Pubmed Central ID:
  PMC5176332
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHSUnited States/
• Volume:
  63
• Issue:
  9
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:93bb9388da7ae2db5cc3d93a947d81f233d1d162d26cc623043af2d2dbd3687f
• Download URL:
  https://stacks.cdc.gov/view/cdc/43319/cdc_43319_DS1.pdf
• File Type:
  [PDF - 99.55 KB ]