Gender Differences in C - reactive protein and Muscle Strengthening Activity

Details

• Alternative Title:
  J Phys Act Health
• Personal Author:
  Richardson, Michael R. ; Johnson, Tammie M. ; Katzmarzyk, Peter T. ; Ford, Earl S. ; Boyer, William R. ; Churilla, James R.
• Description:
  PURPOSE
  
  We sought to examine the gender differences between C-reactive protein (CRP) and muscle strengthening activity (MSA) in U.S. adults (≥20 years of age).
  
  METHODS
  
  The sample (n=9,135) included participants in the 1999–2004 National Health and Nutrition Examination Survey (NHANES). Three categories of reported MSA participation were created: no MSA (referent group), some MSA (≥1 to <2 days/week), and meeting the 2008 Department of Health and Human Services (DHHS) recommendation (≥2 days/week). The dependent variable was elevated CRP (>3 to 10 mg/L).
  
  RESULTS
  
  Gender stratified analysis revealed significantly lower odds of having elevated CRP for women reporting some MSA (OR 0.61; 95% CI 0.45–0.83, P=0.0023), or volumes of MSA meeting the DHHS recommendation (OR 0.66; 95% CI 0.54–0.82, P=0.0004). Significantly lower odds of men having elevated CRP was observed in those reporting MSA volumes meeting the recommendation (OR 0.73; 95% CI 0.61–0.88, P=0.0011). Following adjustment for WC these odds remained significant in men but not women.
  
  CONCLUSIONS
  
  Women reporting any MSA were found to have lower odds of having elevated CRP when compared to those reporting no MSA prior to adjustment for WC. Significantly lower odds in men were only observed in those meeting the recommendation. These results suggest that WC may mediate the associations between MSA and CRP and this relationship may be stronger in women.
  
  
• Subjects:
  Adult Article C-Reactive Protein Exercise Exercise Therapy Female Humans Male Middle Aged Muscle Strength Nutrition Surveys Sex Characteristics Sex Factors Waist Circumference

  More +
• Source:
  J Phys Act Health. 12(12):1582-1588.
• Pubmed ID:
  26963135
• Pubmed Central ID:
  PMC5100671
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHS/United States
• Place as Subject:
  United States
• Volume:
  12
• Issue:
  12
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:4d6c1cbdb80700bc8adf488427be6cde1bc6d1dbb4af82eb85f624267eaa5069
• Download URL:
  https://stacks.cdc.gov/view/cdc/43153/cdc_43153_DS1.pdf
• File Type:
  [PDF - 86.61 KB ]