Autism Symptoms across Adulthood in Men with Fragile X Syndrome: A Cross-sectional Analysis

Details

• Alternative Title:
  J Autism Dev Disord
• Personal Author:
  Hartley, Sigan L. ; Wheeler, Anne C. ; Mailick, Marsha R ; Raspa, Melissa ; Mihaila, Iulia ; Bishop, Ellen ; Bailey, Donald B.
• Description:
  A cross-sectional analysis was used to examine age-related differences in ASD symptoms and corresponding differences in disruptive behavior and social skills in 281 adult men with fragile X syndrome. Four age groups were created: 18-21, 22-29, 30-39, and 40-49 years. The 18-21 year-old group was reported to have more impairments in verbal communication than the 22-29 year-old group and more restricted and repetitive behaviors than the 40-49 year-old group. There was not an age-group difference in the percentage of men who met criteria for an ASD diagnosis based on respondent-reported, current symptoms. There was a trend for an age-related difference in disruptive behavior. Findings add to understanding of the developmental trajectory of ASD symptoms in adulthood.
• Subjects:
  Adolescent Adult Aging Article Autism Autism Spectrum Disorder Communication Cross-Sectional Studies DSM Fragile X Syndrome Humans Male Middle Aged Problem Behavior Social Skills Young Adult

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• Source:
  J Autism Dev Disord. 45(11):3668-3679.
• Pubmed ID:
  26123010
• Pubmed Central ID:
  PMC4609597
• Document Type:
  Journal Article
• Funding:
  P30 HD003352/HD/NICHD NIH HHS/United States ; U01 DD000231/DD/NCBDD CDC HHS/United States ; P30 HD03352/HD/NICHD NIH HHS/United States
• Volume:
  45
• Issue:
  11
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:e777e6bd6a6f731d8f523450e92bba86d57892db4bd03c6bd7a009cdbd8011f3
• Download URL:
  https://stacks.cdc.gov/view/cdc/42075/cdc_42075_DS1.pdf
• File Type:
  [PDF - 330.33 KB ]