Parent Training: Equivalent Improvement in Externalizing Behavior for Children With and Without Familial Risk
Published Date:Jun 21 2014
Source:J Am Acad Child Adolesc Psychiatry. 2014; 53(8):879-887.e2.
Antisocial Personality Disorder
Genetic Predisposition To Disease
Meta-Analysis As Topic
Randomized Controlled Trials As Topic
Receptors, Dopamine D4
Pubmed Central ID:PMC4492282
Funding:R01 NR001075/NR/NINR NIH HHS/United States
R49 CE001510/CE/NCIPC CDC HHS/United States
5 R01 NR01075-11/NR/NINR NIH HHS/United States
MH00988/MH/NIMH NIH HHS/United States
The Incredible Years® Series (IY®) intervention has demonstrated efficacy for reduction in conduct disorder (CD) symptomatology among clinically-affected youth in multiple randomized controlled trials (RCTs). Since children with family psychiatric histories of antisocial behavior are at markedly elevated risk for enduring symptoms of antisocial behavior (in comparison with their family-history-negative counterparts), we examined whether intervention effects across studies prevail in that subgroup or are relatively restricted to children without inferred risk.
We conducted a re-analysis of 5 RCTs of IY® involving 280 clinically-affected children, 3–8 years of age, for whom family psychiatric history of externalizing behavior among first- and second-degree relatives was ascertained from at least 1 parent.
IY® equally benefitted children with CD with and without family psychiatric histories of externalizing behavior. Both family psychiatric history of externalizing behavior and parental depressive symptomatology predicted higher severity of CD symptomatology at baseline.
The beneficial effects of IY® are evident among children with CD, irrespective of whether their conditions are more or less attributable to inherited susceptibility to enduring antisocial syndromes. A next phase of research should address whether earlier implementation of group-based education for parents of young children at elevated familial risk for antisocial behavior syndromes—prior to the development of disruptive patterns of behavior--would result in even more pronounced effects, and thereby constitute cost-effective, targeted preventive intervention for CD.
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