Welcome to CDC stacks | Influence of farming exposure on the development of asthma and asthma-like symptoms - 42000 | CDC Public Access
Stacks Logo
Advanced Search
Select up to three search categories and corresponding keywords using the fields to the right. Refer to the Help section for more detailed instructions.
Clear All Simple Search
Advanced Search
Influence of farming exposure on the development of asthma and asthma-like symptoms
Filetype[PDF-868.43 KB]

  • Pubmed ID:
  • Pubmed Central ID:
  • Description:
    Based upon age and type of farming exposures, a wide range of studies demonstrate either protective or deleterious effects of the farming environment on asthma. In this review, we highlight key studies supporting the concept that farming exposure protects children from asthma and atopy based on studies performed largely in European pediatric cohorts. Various types of farming in certain regions appear to have a greater effect on asthma protection, as does the consumption of unpasteurized milk. In the United State, where concentrated animal feeding operations (CAFOs) are more common, asthma is increased in children exposed especially to swine CAFOs; whereas, rates of atopy and allergy are lower in these children. We also review studies evaluating the role of farming exposures both as a child and/or as an adult on asthma seen in adults. The importance of microbes in farming environments and the contribution of various components of the innate immune system including toll-like receptors to the underlying mechanisms of asthma related to farming exposures are also reviewed.

  • Document Type:
  • Collection(s):
  • Funding:
    R01 ES019325/ES/NIEHS NIH HHS/United States
    R01 OH008539/OH/NIOSH CDC HHS/United States
No Related Documents.
You May Also Like: