Indoor and Outdoor Air Pollution and Lung Cancer in New Hampshire and Vermont

Details

• Alternative Title:
  Toxicol Environ Chem
• Personal Author:
  Sloan, Chantel D. ; Andrew, Angeline S. ; Gruber, Joann F. ; Mwenda, Kevin M. ; Moore, Jason H. ; Onega, Tracy ; Karagas, Margaret R. ; Shi, Xun ; Duell, Eric J. ; Sloan, Chantel D. ; Andrew, Angeline S. ; Gruber, Joann F. ; Mwenda, Kevin M. ; Moore, Jason H. ; Onega, Tracy ; Karagas, Margaret R. ; Shi, Xun ; Duell, Eric J.
• Description:
  Indoor and outdoor air pollution is known to contribute to increased lung cancer incidence. This study is the first to address the contribution of home heating fuel and geographical course particulate matter (PM|) concentrations to lung cancer rates in New Hampshire, U.S. First, Pearson correlation analysis and Geographically weighted regression were used to investigate spatial relationships between outdoor PM| and lung cancer rates. While the aforementioned analyses did not indicate a significant contribution of PM| to lung cancer in the state, there was a trend towards a significant association in the northern and southwestern regions of the state. Second, case-control data were used to estimate the contributions of indoor pollution and second hand smoke to risk of lung cancer with adjustment for confounders. Increased risk was found among those who used wood or coal to heat their homes for more than 10 winters before the age of 18, with a significant increase in risk per winter. Resulting data suggest that further investigation of the relationship between heating-related air pollution levels and lung cancer risk is needed.
• Subjects:
  Article
• Source:
  Toxicol Environ Chem. 94(3) ; Toxicol Environ Chem. 94(3)
• Pubmed ID:
  24273369
• Pubmed Central ID:
  PMC3834966
• Document Type:
  Journal Article
• Funding:
  P20 GM103534/GM/NIGMS NIH HHSUnited States/ ; R01 LM010098-04/LM/NLM NIH HHSUnited States/ ; K07 CA102327-05/CA/NCI NIH HHSUnited States/ ; P20 RR018787/RR/NCRR NIH HHSUnited States/ ; R01 LM009012-07/LM/NLM NIH HHSUnited States/ ; R01 LM009012/LM/NLM NIH HHSUnited States/ ; P20 RR024475/RR/NCRR NIH HHSUnited States/ ; P20 RR018787-09/RR/NCRR NIH HHSUnited States/ ; P42 ES007373/ES/NIEHS NIH HHSUnited States/ ; U58 DP000798/DP/NCCDPHP CDC HHSUnited States/ ; K07 CA102327/CA/NCI NIH HHSUnited States/ ; R01 LM010098/LM/NLM NIH HHSUnited States/
• Volume:
  94
• Issue:
  3
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:ef4cbe8044d33a1698da59fadad33a9e2e444b558217578e4619052f5dc26422
• Download URL:
  https://stacks.cdc.gov/view/cdc/41925/cdc_41925_DS1.pdf
• File Type:
  [PDF - 1.15 MB ]