i
Addressing poor retention of infants exposed to HIV: a quality improvement study in rural Mozambique
-
Jun 1 2012
-
-
Source: J Acquir Immune Defic Syndr. 60(2):e46-e52.
Details:
-
Alternative Title:J Acquir Immune Defic Syndr
-
Personal Author:
-
Description:Objective
Early infant diagnosis (EID) is the first step in HIV care, yet 75% of HIV-exposed infants born at two hospitals in Mozambique failed to access EID.
Design
Before/after study.
Setting
Two district hospitals in rural Mozambique.
Participants
HIV-infected mother/HIV-exposed infant pairs (N=791).
Intervention
We planned two phases of improvement using quality improvement methods. In Phase 1, we enhanced referral by offering direct accompaniment of new mothers to the EID suite, increasing privacy, and opening a medical record for infants prior to post-partum discharge. In Phase 2, we added enhanced referral activity as an item on the maternity register to standardize the process of referral.
Main outcome measure(s)
The proportion of HIV-infected mothers who accessed EID for their infant <90 days of life.
Results
We tracked mother/infant pairs from June 2009 to March 2011 (Phase 0: N=144; Phase 1: N=479; Phase 2: N=168), compared study measures for mother/infant pairs across intervention phases with chi-square, estimated time-to-EID by Kaplan-Meier, and determined the likelihood of EID by Cox regression after adjusting for likely barriers to follow-up. At baseline (phase 0), 25.7% of infants accessed EID <90 days. EID improved to 32.2% after Phase 1; only 17.3% received enhanced referral. After Phase 2, 61.9% received enhanced referral and 39.9% accessed EID, a significant three-phase improvement (p=0.007). In adjusted analysis, the likelihood of EID at any time was higher in the Phase 2 group vs. Phase 0 (aHR:1.68, 95%CI:1.19-2.37, p=0.003).
Conclusions
Retention improved by 55% with a simple referral enhancement. Quality improvement efforts could help improve care in Mozambique and other low-resource countries.
-
Subjects:
-
Source:
-
Pubmed ID:22622077
-
Pubmed Central ID:PMC3587032
-
Document Type:
-
Funding:
-
Place as Subject:
-
Collection(s):
-
Main Document Checksum:
-
Download URL:
-
File Type: