Full-Genome Sequence of a Neuroinvasive West Nile Virus Lineage 2 Strain from a Fatal Horse Infection in South Africa

Mentoor, Juliet L. D.; Lubisi, Alison B.; Gerdes, Truuska; Human, Stacey; Williams, June H.; Venter, Marietjie

doi:10.1128/genomeA.00740-16

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Full-Genome Sequence of a Neuroinvasive West Nile Virus Lineage 2 Strain from a Fatal Horse Infection in South Africa

Jul 28 2016
By Mentoor, Juliet L. D. ; Lubisi, Alison B. ; Gerdes, Truuska ; ...
http://dx.doi.org/10.1128/genomeA.00740-16
Source: Genome Announc. 2016; 4(4).

[PDF-142.67 KB]

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Details:

Alternative Title:

Genome Announc
Personal Author:

Mentoor, Juliet L. D. ; Lubisi, Alison B. ; Gerdes, Truuska ; Human, Stacey ; Williams, June H. ; ... More +

Mentoor, Juliet L. D. ; Lubisi, Alison B. ; Gerdes, Truuska ; Human, Stacey ; Williams, June H. ; Venter, Marietjie Less -
Description:

We report here the complete genome sequence of a lineage 2 West Nile virus (WNV) strain that resulted in fatal neurological disease in a horse in South Africa. Several recent reports exist of neurological disease associated with lineage 2 WNV in humans and horses in South Africa and Europe; however, there are a lack of sequencing data from recent fatal cases in Southern Africa, where these strains likely originate. A better understanding of the genetic composition of highly neuroinvasive lineage 2 strains may facilitate the identification of putative genetic factors associated with increased virulence.
Subjects:

[+]

Viruses
Source:

Genome Announc. 2016; 4(4).
Pubmed ID:

27469963
Pubmed Central ID:

PMC4966467
Document Type:

Journal Article
Collection(s):

CDC Public Access
Main Document Checksum:

[+]

urn:sha256:ea2e9a40bae0ec8b2fea456749dd1dff1311a4f71c614c785c16df6370c23a24
Download URL:

https://stacks.cdc.gov/view/cdc/41581/cdc_41581_DS1.pdf
File Type:

e00740-16.nxml

bin

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