Details:

Alternative Title:
J Wildl Dis
Personal Author:
Amman, Brian R. ; Albariño, Cesar G. ; Bird, Brian H. ; Nyakarahuka, Luke ; Sealy, Tara K. ; ... More +
Amman, Brian R. ; Albariño, Cesar G. ; Bird, Brian H. ; Nyakarahuka, Luke ; Sealy, Tara K. ; Balinandi, Stephen ; Schuh, Amy J. ; Campbell, Shelly M. ; Ströher, Ute ; Jones, Megan E. B. ; Vodzack, Megan E. ; Reeder, DeeAnn M. ; Kaboyo, Winyi ; Nichol, Stuart T. ; Towner, Jonathan S. Less -
Description:
In August 2012, a wildlife biologist became ill immediately following a 6-wk field trip to collect bats and rodents in South Sudan and Uganda. After returning to the US, the biologist was admitted to the hospital with multiple symptoms including fever, malaise, headache, generalized myalgia and arthralgia, stiffness in the neck, and sore throat. Soon after admission, the patient developed a maculopapular rash and oropharynx ulcerations. The patient remained hospitalized for 14 d. Several suspect pathogens, including viral hemorrhagic fever viruses such as Ebola viruses and Marburg viruses, were ruled out through standard diagnostic testing. However, deep sequencing and metagenomic analyses identified a novel paramyxovirus, later named Sosuga virus, in the patient's blood. To determine the potential source, bat tissues collected during the 3-wk period just prior to the onset of symptoms were tested for Sosuga virus, and several Egyptian rousette bats (Rousettus aegyptiacus) were found to be positive. Further analysis of archived Egyptian rousette tissues collected at other localities in Uganda found additional Sosuga virus-positive bats, suggesting this species could be a potential natural reservoir for this novel paramyxovirus.
Subject:
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Animals Animals, Wild Article Bats Chiroptera Female Humans Male Paramyxoviridae Paramyxoviridae Infections Paramyxovirus Phylogeny Reverse Transcriptase Polymerase Chain Reaction Rousettus Aegyptiacus Sosuga Virus Spillover Uganda Wildlife Biologist
Source:
J Wildl Dis. 51(3):774-779
Pubmed ID:
25919464
Pubmed Central ID:
PMC5022529
Document Type:
Journal Article
Funding:
CC999999/Intramural CDC HHS/United States
Place as Subject:
Uganda
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:310595d2f9c174954594ebd166f4cccf228a8cae25ccf4b3fa18f8e1445a8a3c
Download URL:
https://stacks.cdc.gov/view/cdc/41331/cdc_41331_DS1.pdf
File Type:

Supporting Files

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