A Recently Discovered Pathogenic Paramyxovirus, Sosuga Virus, is Present in Rousettus aegyptiacus Fruit Bats at Multiple Locations in Uganda

Amman, Brian R.; Albariño, Cesar G.; Bird, Brian H.; Nyakarahuka, Luke; Sealy, Tara K.; Balinandi, Stephen; Schuh, Amy J.; Campbell, Shelly M.; Ströher, Ute; Jones, Megan E. B.; Vodzack, Megan E.; Reeder, DeeAnn M.; Kaboyo, Winyi; Nichol, Stuart T.; Towner, Jonathan S.

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A Recently Discovered Pathogenic Paramyxovirus, Sosuga Virus, is Present in Rousettus aegyptiacus Fruit Bats at Multiple Locations in Uganda

Published Date:

April 28 2015

Source:

J Wildl Dis. 51(3):774-779

Language:

English

[PDF-431.59 KB]

Details:

Alternative Title:

J Wildl Dis

Personal Author:

Amman, Brian R. ; Albariño, Cesar G. ; Bird, Brian H. ; Nyakarahuka, Luke ; Sealy, Tara K. ; ... More ▼

Description:

In August 2012, a wildlife biologist became ill immediately following a 6-wk field trip to collect bats and rodents in South Sudan and Uganda. After returning to the US, the biologist was admitted to the hospital with multiple symptoms including fever, malaise, headache, generalized myalgia and arthralgia, stiffness in the neck, and sore throat. Soon after admission, the patient developed a maculopapular rash and oropharynx ulcerations. The patient remained hospitalized for 14 d. Several suspect pathogens, including viral hemorrhagic fever viruses such as Ebola viruses and Marburg viruses, were ruled out through standard diagnostic testing. However, deep sequencing and metagenomic analyses identified a novel paramyxovirus, later named Sosuga virus, in the patient's blood. To determine the potential source, bat tissues collected during the 3-wk period just prior to the onset of symptoms were tested for Sosuga virus, and several Egyptian rousette bats (Rousettus aegyptiacus) were found to be positive. Further analysis of archived Egyptian rousette tissues collected at other localities in Uganda found additional Sosuga virus-positive bats, suggesting this species could be a potential natural reservoir for this novel paramyxovirus.

Subject:

[+]

Pubmed ID:

25919464

Pubmed Central ID:

PMC5022529

Document Type:

Journal Article

Funding:

CC999999/Intramural CDC HHS/United States

Place as Subject:

Uganda

Collection(s):

CDC Public Access

Main Document Checksum:

[+]

Supporting Files:

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