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Mutation in West Nile Virus Structural Protein prM during Human Infection
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Sep 15 2016
Source: Emerg Infect Dis. 22(9):1647-1649. -
Alternative Title:Emerg Infect Dis
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Description:A mutation leading to substitution of a key amino acid in the prM protein of West Nile virus (WNV) occurred during persistent infection of an immunocompetent patient. WNV RNA persisted in the patient's urine and serum in the presence of low-level neutralizing antibodies. This case demonstrates active replication of WNV during persistent infection.
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Pubmed ID:27322782
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Pubmed Central ID:PMC4994336
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