Multidrug-Resistant Shigella Infections in Patients with Diarrhea, Cambodia, 2014–2015

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Poramathikul, Kamonporn ; Bodhidatta, Ladaporn ; Chiek, Sivhour ; Oransathid, Wilawan ; Ruekit, Sirigade ; Nobthai, Panida ; Lurchachaiwong, Woradee ; Serichantalergs, Oralak ; Lon, Chanthap ; Swierczewski, Brett
• Description:
  We observed multidrug resistance in 10 (91%) of 11 Shigella isolates from a diarrheal surveillance study in Cambodia. One isolate was resistant to fluoroquinolones and cephalosporins and showed decreased susceptibility to azithromycin. We found mutations in gyrA, parC, β-lactamase, and mphA genes. Multidrug resistance increases concern about shigellosis treatment options.
• Subjects:
  Adolescent Adult Anti-Bacterial Agents Child, Preschool Diarrhea/Drug Therapy Diarrhea/Epidemiology Diarrhea/History Diarrhea/Microbiology Drug Resistance, Multiple, Bacterial Dysentery, Bacillary/Drug Therapy Dysentery, Bacillary/Epidemiology Dysentery, Bacillary/History Dysentery, Bacillary/Microbiology Female Genes, Bacterial History, 21St Century Humans Infant Male Microbial Sensitivity Tests Middle Aged Mutation Population Surveillance Shigella Young Adult

  More +
• Source:
  Emerg Infect Dis. 22(9):1640-1643.
• Pubmed ID:
  27532684
• Pubmed Central ID:
  PMC4994341
• Document Type:
  Journal Article
• Genre:
  Historical Article
• Place as Subject:
  Cambodia
• Location:
  Asia
• Volume:
  22
• Issue:
  9
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:6294b4525e353ba09d120841f3f3d7ac80788729db8c1470715183bc52150310
• Download URL:
  https://stacks.cdc.gov/view/cdc/41250/cdc_41250_DS1.pdf
• File Type:
  [PDF - 1.58 MB ]