Outbreak of Achromobacter xylosoxidans and Ochrobactrum anthropi Infections after Prostate Biopsies, France, 2014

Haviari, Skerdi; Cassier, Pierre; Dananché, Cédric; Hulin, Monique; Dauwalder, Olivier; Rouvière, Olivier; Bertrand, Xavier; Perraud, Michel; Bénet, Thomas; Vanhems, Philippe

doi:10.3201/eid2208.151423

i

Outbreak of Achromobacter xylosoxidans and Ochrobactrum anthropi Infections after Prostate Biopsies, France, 2014

Supporting Files Public Domain

Aug 2016
By Haviari, Skerdi ; Cassier, Pierre ; Dananché, Cédric ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Haviari, Skerdi ; Cassier, Pierre ; Dananché, Cédric ; Hulin, Monique ; Dauwalder, Olivier ; Rouvière, Olivier ; Bertrand, Xavier ; Perraud, Michel ; Bénet, Thomas ; Vanhems, Philippe
Description:

We report an outbreak of healthcare-associated prostatitis involving rare environmental pathogens in immunocompetent patients undergoing transrectal prostate biopsies at Hôpital Édouard Herriot (Lyon, France) during August 13-October 10, 2014. Despite a fluoroquinolone-based prophylaxis, 5 patients were infected with Achromobacter xylosoxidans and 3 with Ochrobactrum anthropi, which has not been reported as pathogenic in nonimmunocompromised persons. All patients recovered fully. Analysis of the outbreak included case investigation, case-control study, biopsy procedure review, microbiologic testing of environmental and clinical samples, and retrospective review of hospital records for 4 years before the outbreak. The cases resulted from asepsis errors during preparation of materials for the biopsies. A low-level outbreak involving environmental bacteria was likely present for years, masked by antimicrobial drug prophylaxis and a low number of cases. Healthcare personnel should promptly report unusual pathogens in immunocompetent patients to infection control units, and guidelines should explicitly mention asepsis during materials preparation.
Subjects:

Achromobacter Denitrificans Biopsy/adverse Effects Case-Control Studies Disease Outbreaks Equipment Contamination Gram-Negative Bacterial Infections/etiology Gram-Negative Bacterial Infections/microbiology Humans Male Ochrobactrum Anthropi Prostatic Diseases/microbiology Prostatic Diseases/pathology Research Surgical Equipment
Source:

Emerg Infect Dis. 22(8):1412-1419.
Pubmed ID:

27434277
Pubmed Central ID:

PMC4982167
Document Type:

Journal Article
Place as Subject:

France
Location:

Europe
Volume:

22
Issue:

8
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:27f8ad1b545a8f079daf1751d6d9a1de9d0784e3336a645568d9d254ecaf0bb9
Download URL:

https://stacks.cdc.gov/view/cdc/40845/cdc_40845_DS1.pdf
File Type:

[PDF - 900.02 KB ]

File Language:

English

ON THIS PAGE

Details Supporting Files

CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners.

As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.