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Middle East Respiratory Syndrome
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  1. Surveillance and Testing for Middle East Respiratory Syndrome Coronavirus, Saudi Arabia, March 2016–March 2019
    Personal Author:
    Alzahrani, Abdullah; Kujawski, Stephanie A.; Abedi, Glen R.; Tunkar, Safaa; Biggs, Holly M.; Alghawi, Nada; Jokhdar, Hani; Assiri, Abdullah M.; Watson, John T.;
    Published Date:
    Jul 2020
    Source:
    Emerg Infect Dis. 26(7):1571-1574
    Description:
    During March 2016-March 2019, a total of 200,936 suspected cases of Middle East respiratory syndrome coronavirus infection were identified in Saudi Arabia; infections were confirmed in 698 cases (0.3% [0.7/100,000 population per year]). Continued sur...
    File Type:
    Filetype[PDF - 753.07 KB]
  2. Serologic Detection of Middle East Respiratory Syndrome Coronavirus Functional Antibodies
    Personal Author:
    Okba, Nisreen M.A.; Widjaja, Ivy; Li, Wentao; GeurtsvanKessel, Corine H.; Farag, Elmoubasher A.B.A.; Al-Hajri, Mohammed; Park, Wan Beom; Oh, Myoung-don; Reusken, Chantal B.E.M.; Koopmans, Marion P.G.; Bosch, Berend-Jan; Haagmans, Bart L.;
    Published Date:
    May 17 2020
    Source:
    Emerg Infect Dis. 26(5):1024-1027
    Description:
    We developed and validated 2 species-independent protein-based assays to detect Middle East respiratory syndrome coronavirus functional antibodies that can block virus receptor-binding or sialic acid-attachment. Antibody levels measured in both assay...
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    Filetype[PDF - 1.34 MB]
  3. Auspicious Symbols of Rank and Status
    Personal Author:
    Breedlove, Byron; Fung, Isaac Chun-Hai;
    Published Date:
    May 2020
    Source:
    Emerg Infect Dis. 26(5):1056-1057
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  4. Etymologia: Coronavirus
    Personal Author:
    Henry, Ronnie
    Published Date:
    May 2020
    Source:
    Emerg Infect Dis. 26(5):1027
    Description:
    The first coronavirus, avian infectious bronchitis virus, was discovered in 1937 by Fred Beaudette and Charles Hudson. In 1967, June Almeida and David Tyrrell per-formed electron microscopy on specimens from cultures of viruses known to cause colds i...
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  5. An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice
    Personal Author:
    Sheahan, Timothy P.; Sims, Amy C.; Zhou, Shuntai; Graham, Rachel L.; Pruijssers, Andrea J.; Agostini, Maria L.; Leist, Sarah R.; Schäfer, Alexandra; Dinnon, Kenneth H.; Stevens, Laura J.; Chappell, James D.; Lu, Xiaotao; Hughes, Tia M.; George, Amelia S.; Hill, Collin S.; Montgomery, Stephanie A.; Brown, Ariane J.; Bluemling, Gregory R.; Natchus, Michael G.; Saindane, Manohar; Kolykhalov, Alexander A.; Painter, George; Harcourt, Jennifer; Tamin, Azaibi; Thornburg, Natalie J.; Swanstrom, Ronald; Denison, Mark R.; Baric, Ralph S.;
    Published Date:
    April 06 2020
    Source:
    Sci Transl Med. 2020; 12(541)
    Description:
    Coronaviruses (CoVs) traffic frequently between species resulting in novel disease outbreaks, most recently exemplified by the newly emerged SARS-CoV-2, the causative agent of COVID-19. Here, we show that the ribonucleoside analog β-d-N|-hydroxycyti...
    File Type:
    Filetype[PDF - 511.02 KB]