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Time From HIV Diagnosis to Viral Load Suppression: 2007–2013
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Details:
  • Pubmed ID:
    26650994
  • Pubmed Central ID:
    PMC4902572
  • Description:
    Background

    US guidelines now recommend that all HIV-infected persons receive antiretroviral therapy). HIV prevention is increasingly focused on ensuring that infected persons are diagnosed soon after HIV acquisition and quickly link to care and initiate antiretroviral therapy. We examined trends in time from HIV diagnosis to viral load suppression in King County, WA, to gauge improvement in our HIV care continuum over time.

    Methods

    We used HIV surveillance data and Cox proportional hazards to evaluate how the time from diagnosis to viral suppression changed among persons newly diagnosed as having HIV in King County, WA, between 2007 and 2013.

    Results

    A total of 1490 (84%) of 1766 newly diagnosed persons achieved viral suppression in a median time of 213 days (95% confidence interval, 203–229). Thirty-six percent of all persons diagnosed in 2007 and 77% in 2013 were virally suppressed within 12 months of HIV diagnosis (P < 0.0001). Differences in time to suppression by calendar year persisted when stratifying by CD4 count at diagnosis. Race was not significantly associated with time to viral suppression.

    Conclusions

    Time from HIV diagnosis to viral suppression dramatically declined between 2007 and 2013, and more than three quarters of recently HIV-diagnosed individuals in King County, WA, now achieve viral suppression within a year of diagnosis. This improvement was evident among all persons newly diagnosed as having HIV, regardless of race/ethnicity or CD4 count at time of diagnosis.

  • Document Type:
  • Collection(s):
  • Funding:
    CDC-RFA-PS13-130202/PS/NCHHSTP CDC HHS/United States
    K23 MH090923/MH/NIMH NIH HHS/United States
    L30 MH095060/MH/NIMH NIH HHS/United States
    P30AI027757/AI/NIAID NIH HHS/United States
    R21 HD080523/HD/NICHD NIH HHS/United States
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