Time From HIV Diagnosis to Viral Load Suppression: 2007–2013

Details

• Alternative Title:
  Sex Transm Dis
• Personal Author:
  Toren, Katelynne Gardner ; Buskin, Susan E. ; Dombrowski, Julia C. ; Cassels, Susan L. ; Golden, Matthew R.
• Description:
  Background
  
  US guidelines now recommend that all HIV-infected persons receive antiretroviral therapy). HIV prevention is increasingly focused on ensuring that infected persons are diagnosed soon after HIV acquisition and quickly link to care and initiate antiretroviral therapy. We examined trends in time from HIV diagnosis to viral load suppression in King County, WA, to gauge improvement in our HIV care continuum over time.
  
  Methods
  
  We used HIV surveillance data and Cox proportional hazards to evaluate how the time from diagnosis to viral suppression changed among persons newly diagnosed as having HIV in King County, WA, between 2007 and 2013.
  
  Results
  
  A total of 1490 (84%) of 1766 newly diagnosed persons achieved viral suppression in a median time of 213 days (95% confidence interval, 203–229). Thirty-six percent of all persons diagnosed in 2007 and 77% in 2013 were virally suppressed within 12 months of HIV diagnosis (P < 0.0001). Differences in time to suppression by calendar year persisted when stratifying by CD4 count at diagnosis. Race was not significantly associated with time to viral suppression.
  
  Conclusions
  
  Time from HIV diagnosis to viral suppression dramatically declined between 2007 and 2013, and more than three quarters of recently HIV-diagnosed individuals in King County, WA, now achieve viral suppression within a year of diagnosis. This improvement was evident among all persons newly diagnosed as having HIV, regardless of race/ethnicity or CD4 count at time of diagnosis.
  
  
• Subjects:
  Adolescent Adult Anti-HIV Agents CD4 Lymphocyte Count Continuity Of Patient Care Female HIV Infections Humans Male Middle Aged Population Surveillance Time-to-Treatment Viral Load Young Adult

  More +
• Source:
  Sex Transm Dis. 43(1):34-40.
• Pubmed ID:
  26650994
• Pubmed Central ID:
  PMC4902572
• Document Type:
  Journal Article
• Funding:
  CDC-RFA-PS13-130202/PS/NCHHSTP CDC HHS/United States ; K23 MH090923/MH/NIMH NIH HHS/United States ; L30 MH095060/MH/NIMH NIH HHS/United States ; P30AI027757/AI/NIAID NIH HHS/United States ; R21 HD080523/HD/NICHD NIH HHS/United States
• Volume:
  43
• Issue:
  1
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:169cf741f25672308e8c28d47a43b5ef92e737bbb4436b8e4fa0afef92a26371
• Download URL:
  https://stacks.cdc.gov/view/cdc/39863/cdc_39863_DS1.pdf
• File Type:
  [PDF - 233.43 KB ]