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Human Infection with Influenza A(H7N9) Virus during 3 Major Epidemic Waves, China, 2013–2015
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Jun 2016
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Source: Emerg Infect Dis. 22(6):964-972.
[PDF-2.99 MB]
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Alternative Title:Emerg Infect Dis
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Description:Since March 2013, a novel influenza A(H7N9) virus has caused 3 epidemic waves of human infection in mainland China. We analyzed data from patients with laboratory-confirmed influenza A(H7N9) virus infection to estimate the risks for severe outcomes after hospitalization across the 3 waves. We found that hospitalized patients with confirmed infections in waves 2 and 3 were younger and more likely to be residing in small cities and rural areas than were patients in wave 1; they also had a higher risk for death, after adjustment for age and underlying medical conditions. Risk for death among hospitalized patients during waves 2 and 3 was lower in Jiangxi and Fujian Provinces than in eastern and southern provinces. The variation in risk for death among hospitalized case-patients in different areas across 3 epidemic waves might be associated with differences in case ascertainment, changes in clinical management, or virus genetic diversity.
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Pubmed ID:27191934
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Pubmed Central ID:PMC4880089
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Volume:22
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Issue:6
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