Human Infection with Influenza A(H7N9) Virus during 3 Major Epidemic Waves, China, 2013–2015

Wu, Peng; Peng, Zhibin; Fang, Vicky J.; Feng, Luzhao; Tsang, Tim K.; Jiang, Hui; Lau, Eric H.Y.; Yang, Juan; Zheng, Jiandong; Qin, Ying; Li, Zhongjie; Leung, Gabriel M.; Yu, Hongjie; Cowling, Benjamin J.

doi:10.3201/eid2206.151752

i

Human Infection with Influenza A(H7N9) Virus during 3 Major Epidemic Waves, China, 2013–2015

Supporting Files Public Domain

Jun 2016
By Wu, Peng ; Peng, Zhibin ; Fang, Vicky J. ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Wu, Peng ; Peng, Zhibin ; Fang, Vicky J. ; Feng, Luzhao ; Tsang, Tim K. ; Jiang, Hui ; Lau, Eric H.Y. ; Yang, Juan ; Zheng, Jiandong ; Qin, Ying ; Li, Zhongjie ; Leung, Gabriel M. ; Yu, Hongjie ; Cowling, Benjamin J.
Description:

Since March 2013, a novel influenza A(H7N9) virus has caused 3 epidemic waves of human infection in mainland China. We analyzed data from patients with laboratory-confirmed influenza A(H7N9) virus infection to estimate the risks for severe outcomes after hospitalization across the 3 waves. We found that hospitalized patients with confirmed infections in waves 2 and 3 were younger and more likely to be residing in small cities and rural areas than were patients in wave 1; they also had a higher risk for death, after adjustment for age and underlying medical conditions. Risk for death among hospitalized patients during waves 2 and 3 was lower in Jiangxi and Fujian Provinces than in eastern and southern provinces. The variation in risk for death among hospitalized case-patients in different areas across 3 epidemic waves might be associated with differences in case ascertainment, changes in clinical management, or virus genetic diversity.
Subjects:

Adolescent Adult Aged Aged, 80 And Over Animals Child Child, Preschool Disease Outbreaks Female Genotype Geography, Medical History, 21St Century Hospitalization Humans Infant Infant, Newborn Influenza, Human/Epidemiology Influenza, Human/History Influenza, Human/Transmission Influenza, Human/Virology Influenza A Virus, H7N9 Subtype Male Middle Aged Mortality Population Surveillance Young Adult
Source:

Emerg Infect Dis. 22(6):964-972.
Pubmed ID:

27191934
Pubmed Central ID:

PMC4880089
Document Type:

Journal Article
Place as Subject:

China
Volume:

22
Issue:

6
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:43ec7594f234dceb05f5de100e5f675e21e00db95d5767f0e8872d8911e20ddb
Download URL:

https://stacks.cdc.gov/view/cdc/39689/cdc_39689_DS1.pdf
File Type:

[PDF - 2.99 MB ]

File Language:

English

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