Human Infection with Influenza A(H7N9) Virus during 3 Major Epidemic Waves, China, 2013–2015

Wu, Peng; Peng, Zhibin; Fang, Vicky J.; Feng, Luzhao; Tsang, Tim K.; Jiang, Hui; Lau, Eric H.Y.; Yang, Juan; Zheng, Jiandong; Qin, Ying; Li, Zhongjie; Leung, Gabriel M.; Yu, Hongjie; Cowling, Benjamin J.

doi:10.3201/eid2206.151752

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Human Infection with Influenza A(H7N9) Virus during 3 Major Epidemic Waves, China, 2013–2015

Published Date:

Jun 2016

Publisher's site:

http://dx.doi.org/10.3201/eid2206.151752

Source:

Emerg Infect Dis. 22(6):964-972.

[PDF-2.99 MB]

Details:

Alternative Title:

Emerg Infect Dis

Personal Author:

Wu, Peng ; Peng, Zhibin ; Fang, Vicky J. ; Feng, Luzhao ; Tsang, Tim K. ; ... More ▼

Description:

Since March 2013, a novel influenza A(H7N9) virus has caused 3 epidemic waves of human infection in mainland China. We analyzed data from patients with laboratory-confirmed influenza A(H7N9) virus infection to estimate the risks for severe outcomes after hospitalization across the 3 waves. We found that hospitalized patients with confirmed infections in waves 2 and 3 were younger and more likely to be residing in small cities and rural areas than were patients in wave 1; they also had a higher risk for death, after adjustment for age and underlying medical conditions. Risk for death among hospitalized patients during waves 2 and 3 was lower in Jiangxi and Fujian Provinces than in eastern and southern provinces. The variation in risk for death among hospitalized case-patients in different areas across 3 epidemic waves might be associated with differences in case ascertainment, changes in clinical management, or virus genetic diversity.

Subject:

[+]

Pubmed ID:

27191934

Pubmed Central ID:

PMC4880089

Document Type:

Journal Article

Place as Subject:

China

Collection(s):

Emerging Infectious Diseases

Main Document Checksum:

[+]

Supporting Files:

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